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Submit ReviewSMCy 5.5
Discontinued Product
7295 has been discontinued.
View all Fluorescent Lipid Probes and Cell Membrane Stains products.
Description: Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
Chemical Name: 6,8-Dicyclohexyl-4-((1E,3E,5E)-5-(1,1-dimethyl-3-(pent-4-yn-1-yl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-2,2-difluoro-2,8-dihydro-5H-1λ3,2λ4-[1,3,2]dioxaborinino[6,5-d]pyrimidine-5,7(6H)-dione
Purity: ≥95% (HPLC)
Biological Activity for SMCy 5.5
Key information: SMCy 5.5 is a fluorogenic fluorescent probe for imaging lipid droplets. Supplied with an alkyne reactive handle for click chemistry. Suitable for deep tissue imaging and 3D imaging.
Application: Suitable for 2-photon excitation (2-PE) microscopy. Alkyne handle allows optional functionalization.
Properties and Photophysical Data: SMCy 5.5 exhibits sharp excitation and emission bands and high brightness. It displays high two-photon absorption (TPA) cross-section values (13330 GM and 10400 GM at 770 and 820 nm, respectively). Excitation and emission maxima (λ) for SMCy 5.5 in Tetrahydrofuran are 643nm and 672 nm, respectively; quantum yield = 0.75; extinction coefficient = 209,000 M-1 cm-1.
Optical Data for SMCy 5.5
| Emission Color | Far Red |
|---|---|
| Brightness | |
| λabs | 636 nm |
| λem | 660 nm |
| Extinction Coefficient (ε) | 194,000 M-1cm-1 |
| Quantum Yield (φ) | 1 |
| Closest Laser line | 640 nm |
| Reactive Group | Alkyne |
| Reactivity | Click |
| Cell Permeable | Yes |
| Application | 2PE Fluorescence Imaging, Deep Tissue Imaging, 3D Imaging |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data for SMCy 5.5
| M. Wt | 693.64 |
| Formula | C41H46BF2N3O4 |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 2417507-09-4 |
| InChI Key | CCEAGIQCUXUBGY-GNVKXZRTSA-N |
| Smiles | CC1(/C(N(C2=C1C3=CC=CC=C3C=C2)CCCC#C)=C\C=C\C=C\C4=C(C(N(C(N5C6CCCCC6)=O)C7CCCCC7)=O)C5=[O+][B-](F)(F)O4)C |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for SMCy 5.5
References for SMCy 5.5
References are publications that support the biological activity of the product.
Collot et al (2018) Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues. J.Am.Chem.Soc. 140 5401 PMID: 29446627
Fam et al (2018) Recent advances in fluorescent probes for lipid droplets. Materials (Basel) 11 1768 PMID: 30231571
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Keywords: SMCy 5.5, SMCy 5.5 supplier, Fluorescent, fluorogenic, probe, imaging, lipid, droplets, two-photon, microscopy, 2-photon, Lipid, Probes, and, Cell, Membrane, Stains, 7295, Tocris Bioscience
Citations for SMCy 5.5
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Currently there are no citations for SMCy 5.5.
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Fluorescent Dyes and Probes Research Product GuideUpdated
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including Janelia Fluor® Dyes
- Fluorescent Probes for Advanced Microscopy and Live Cell Imaging
- Fluorescent Probes to Support In Vivo, Deep Tissue, and Bioluminescence Imaging
- Fluorescent Probes and Reagents for Organoids and 3D Cell Culture Imaging
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals
- Tissue Clearing Kits and Reagents