Tocriscreen 2.0 Max

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Cat.No. 7150 - Tocriscreen 2.0 Max
Description: Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 biologically active compounds (250 μL 10 mM DMSO solutions)
Datasheet
Citations (6)
Reviews
Literature (1)

Biological Activity

A library of 1280 biologically active compounds from the Tocris catalog. Covers a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 250 μL 10 mM DMSO solutions. A smaller volume is available as Tocriscreen 2.0 Mini (Cat. No. 7151) and Tocriscreen 2.0 Micro (Cat. No. 7152).

This library replaces the Tocriscreen Plus (Cat. No. 5840).

For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Key Format and Product Details

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Compounds arranged 80 per rack with 16 racks per library
  • Pre-dissolved in DMSO
  • Many compounds are exclusive to Tocris
  • Unique library with low overlap
  • Full chemical and biological data available
  • Exceptional purity
Target Classes Covered by the Tocriscreen 2.0 Compound Library

The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).

Request Compound List

To request a list of the compounds available in the Tocriscreen 2.0 Max please click the request tile below. Compound lists can be provided in Excel or SD format.

Request compound list for Tocriscreen 2.0 Max

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References

References are publications that support the biological activity of the product.

Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196 PMID: 20956998

Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034

Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546 PMID: 20142487

Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201

Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371


If you know of a relevant reference for Tocriscreen 2.0 Max, please let us know.

View Related Products by Target

Keywords: Tocriscreen 2.0 Max, Tocriscreen 2.0 Max supplier, biologically, active, pre-dissolved, DMSO, 250ul, 10mM, solutions, Tocriscreen, Compound, Collections, Screening, Library, Libraries, HTS, HCS, high, throughput, content, 7150, Tocris Bioscience

6 Citations for Tocriscreen 2.0 Max

Citations are publications that use Tocris products. Selected citations for Tocriscreen 2.0 Max include:

Yang et al (2017) Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell 169 243 PMID: 28388409

Tian et al (2020) Discovery and Structure Relationships of Salicylanilide Derivatives as Potent, Non-acidic P2X1 Receptor Antagonists. J Med Chem 63 6164 PMID: 32345019

Telpoukhovskaia et al (2020) Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. Science Reports 10 13688 PMID: 32792571

Danthi et al (2019) Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays. SLAS Discov 24 111 PMID: 30589598


Do you know of a great paper that uses Tocriscreen 2.0 Max from Tocris? Please let us know.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focussed Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service