Phalloidin-Janelia Fluor® 646

Pricing Availability   Qty
Description: Red fluorescent F-actin probe
Alternative Names: Phalloidin-JF646
Purity: ≥90% (HPLC)
Literature (1)

Biological Activity for Phalloidin-Janelia Fluor® 646

Phalloidin-Janelia Fluor® 646 is a red fluorescent F-actin probe. Phalloidin-Janelia Fluor® 646 is composed of the F-actin probe, Phalloidin (Cat. No. 4535), conjugated to Janelia Fluor® 646 (Cat. No. 6148). It is suitable for use in confocal and super-resolution microscopy techniques such as dSTORM. Excitation/emission maximum λ = 646/664 nm.

Licensing Information

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data for Phalloidin-Janelia Fluor® 646

Phalloidin-Janelia Fluor<sup>®</sup> 646 Dye Spectra
Emission Color Red
λabs 646 nm
λem 664 nm
Extinction Coefficient (ε) 152,000 M-1cm-1
Quantum Yield (φ) 0.54
Closest Laser line 640 nm
Application Confocal imaging, dSTORM, STED, Flow Cytometry

Technical Data for Phalloidin-Janelia Fluor® 646

M. Wt 1266.51
Formula C64H75N11O13SSi
Storage Store at -20°C
Purity ≥90% (HPLC)
Smiles O=C([C@H](NC([C@H](C)NC([C@H](C[C@](O)(C)CNC(C1=CC=C(C([O-])=O)C(C2=C(C=C/3)C([Si](C)(C)C4=CC(N5CCC5)=CC=C42)=CC3=[N+]6CCC\6)=C1)=O)N7)=O)=O)[C@H](C)O)N[C@H]8CSC(N9)=C(C[C@H](NC([C@H](C)NC([C@@H]%10C[C@@H](O)CN%10C8=O)=O)=O)C7=O)C%11=C9C=CC=C%11

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Phalloidin-Janelia Fluor® 646

References for Phalloidin-Janelia Fluor® 646

References are publications that support the biological activity of the product.

Grimm et al (2015) A general method to improve fluorophores for live-cell and single-molecule microscopy. Nat.Methods 12 244 PMID: 25599551

Cooper et al (1987) Effects of cytochalasin and phalloidin on actin. J.Cell.Biol. 105 1473 PMID: 3312229

If you know of a relevant reference for Phalloidin-Janelia Fluor® 646, please let us know.

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Citations for Phalloidin-Janelia Fluor® 646

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