NSC 23005 sodium

Discontinued Product

NSC 23005 sodium (Cat. No. 5779) has been withdrawn from sale for commercial reasons.
Description: Potently promotes HSC expansion ; p18INK inhibitor
Chemical Name: 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt
Purity: ≥99% (HPLC)
Literature (4)

Biological Activity for NSC 23005 sodium

NSC 23005 sodium is a p18INK inhibitor. Potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM). Exhibits no effect on leukemia cell proliferation.

Compound Libraries for NSC 23005 sodium

NSC 23005 sodium is also offered as part of the Tocriscreen Stem Cell Library. Find out more about compound libraries available from Tocris.

Technical Data for NSC 23005 sodium

M. Wt 305.33
Formula C13H16NNaO4S
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 1796596-46-7
PubChem ID 122705986
Smiles O=S(C1=CC=C(C([O-])=O)C=C1)(NC2CCCCC2)=O.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for NSC 23005 sodium

References for NSC 23005 sodium

References are publications that support the biological activity of the product.

Xie et al (2015) Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci.Rep. 5 18115 PMID: 26681454

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Citations for NSC 23005 sodium

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Currently there are no citations for NSC 23005 sodium.

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