You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Cognitive enhancer that displays various pharmacological effects. Activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Displays potent neuroprotective action in the retinal ischemia-reperfusion model in vivo.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 246.3. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.06 mL||20.3 mL||40.6 mL|
|5 mM||0.81 mL||4.06 mL||8.12 mL|
|10 mM||0.41 mL||2.03 mL||4.06 mL|
|50 mM||0.08 mL||0.41 mL||0.81 mL|
References are publications that support the biological activity of the product.
Narahashi et al (2004) Mechanisms of action of cognitive enhancers on neuroreceptors. Biol.Pharm.Bull. 27 1701 PMID: 15516710
Ueda et al (2004) The cognitive-enhancer nefiracetam inhibits both necrosis and apoptosis in retinal ischemic models in vitro and in vivo. J.Pharmacol.Exp.Ther. 309 200 PMID: 14718588
Kitano et al (2005) Effects of nefiracetam, a novel pyrrolidone-type nootropic agent, on the amygdala-kindled seizures in rats. Epilepsia 46 1561 PMID: 16190926
If you know of a relevant reference for Nefiracetam, please let us know.
View Related Products by Target
Keywords: Nefiracetam, Nefiracetam supplier, Cognitive, enhancer, activates, L/N-type, Ca2+, channels, potentiates, NMDA, currents, Muscarinic, Receptors, Acetylcholine, Nicotinic, nAChR, Calcium, CaV, Channels, L-Type, N-Type, voltage-gated, voltage-dependent, Glutamate, N-Methyl-D-Aspartate, iGluR, Ionotropic, DM9384, DM, 9384, Other, Cav1.x, Non-selective, Muscarinics, Cav2.x, 2851, Tocris Bioscience
Citations for Nefiracetam
Citations are publications that use Tocris products.
Currently there are no citations for Nefiracetam. Do you know of a great paper that uses Nefiracetam from Tocris? Please let us know.
Reviews for Nefiracetam
There are currently no reviews for this product. Be the first to review Nefiracetam and earn rewards!
Have you used Nefiracetam?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.