You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for NBD-PE
NBD-PE is a fluorescent label for lysosomal lipid bodies. It consists of a single tail (16:0) phospholipid derivative with an NBD fluorophore conjugated to the head group. NBD-PE can be used to quantitatively measure phospholipidosis, which is useful to screen drugs for SARS-CoV-2 repurposing. NBD-PE can also be used to label giant unilamellar vesicles (GUV).
Optical Data for NBD-PE
|Extinction Coefficient (ε)||22000 M-1cm-1|
Technical Data for NBD-PE
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for NBD-PE
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|methanol||0.48||0.5 with sonication|
Preparing Stock Solutions for NBD-PE
The following data is based on the product molecular weight 956.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.005 mM||209.15 mL||1045.74 mL||2091.48 mL|
|0.025 mM||41.83 mL||209.15 mL||418.3 mL|
|0.05 mM||20.91 mL||104.57 mL||209.15 mL|
|0.25 mM||4.18 mL||20.91 mL||41.83 mL|
References for NBD-PE
References are publications that support the biological activity of the product.
Morelli et al (2006) Validation of an in vitroscreen for phospholipidosis using a high-content biology platform. Cell Biol.Toxicol. 22 15 PMID: 16463016
Gum et al (2001) Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes. Biochem.Pharmacol. 62 1661 PMID: 11755120
Li et al (2020) Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays. Nat.Commun. 11 232 PMID: 31932592
Tummino et al (2021) Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2. Science 373 541 PMID: 34326236
If you know of a relevant reference for NBD-PE, please let us know.
View Related Products by Target
Keywords: NBD-PE, NBD-PE supplier, NBDPE, phospholipid, derivative, fluorescence, NBD, label, lysosomal, lipid, bodies, quantitative, quantification, phospholipidosis, giant, unilamellar, vesicles, GUV, drug, screening, SARS-Cov-2, Fluorescent, Lipid, Probes, and, Cell, Membrane, Stains, Lysosome, 7538, Tocris Bioscience
Citations for NBD-PE
Citations are publications that use Tocris products.
Currently there are no citations for NBD-PE. Do you know of a great paper that uses NBD-PE from Tocris? Please let us know.
Reviews for NBD-PE
There are currently no reviews for this product. Be the first to review NBD-PE and earn rewards!
Have you used NBD-PE?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Fluorescent Dyes and Probes Research Product GuideUpdated
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals