Methoxyresorufin

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Cat.No. 4814 - Methoxyresorufin | C13H9NO3 | CAS No. 5725-89-3
Description: Fluorometric CYP450 substrate
Chemical Name: 7-Methoxy-3H-phenoxazin-3-one
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Fluorometric substrate of cytochrome P450; displays preferential metabolism by rodent cytochrome P4501A2 (CYP1A2).

Technical Data

M. Wt 227.22
Formula C13H9NO3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 5725-89-3
PubChem ID 119220
InChI Key KNYYMGDYROYBRE-UHFFFAOYSA-N
Smiles O=C2C=CC1=NC3=C(C=C(OC)C=C3)OC1=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 0.23 1 with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 227.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.01 mM 440.1 mL 2200.51 mL 4401.02 mL
0.05 mM 88.02 mL 440.1 mL 880.2 mL
0.1 mM 44.01 mL 220.05 mL 440.1 mL
0.5 mM 8.8 mL 44.01 mL 88.02 mL

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References

References are publications that support the biological activity of the product.

Nerurkar et al (1993) Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by the cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem.Pharmacol. 46 933 PMID: 8373445


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Keywords: Methoxyresorufin, Methoxyresorufin supplier, cytochrome, P450, CYP4502A1, substrates, fluorometric, fluorimetric, Cytochrome, 4814, Tocris Bioscience

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