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Inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro.
(Modifications: Ala-1 = Z-Ala, X-5= 3-Cyclopentyl-L-alanine, Arg-21= C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 2 mg/ml in water|
References are publications that support the biological activity of the product.
Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID: 28759015
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Keywords: MAIT 203, MAIT 203 supplier, MAIT203, APC, Asef, interaction, inhibitors, inhibits, colorectal, cancer, migration, Rho, 6382, Tocris Bioscience
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