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Submit ReviewMAIT 203
Discontinued Product
MAIT 203 (Cat. No. 6382) has been withdrawn from sale for commercial reasons.
Description: APC-Asef (RhoGEF4) interaction inhibitor
Biological Activity for MAIT 203
MAIT 203 is an inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro.
Technical Data for MAIT 203
| M. Wt | 2517.83 |
| Formula | C106H177N43O29 |
| Sequence |
AGEAXYEGGGGGRKKRRQRRR (Modifications: Ala-1 = Z-Ala, X-5= 3-Cyclopentyl-L-alanine, Arg-21= C-terminal amide) |
| Storage | Store at -20°C |
| PubChem ID | 132470912 |
| InChI Key | BWXFXXHBUFJJSA-YLOXEXSPSA-N |
| Smiles | C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for MAIT 203
References for MAIT 203
References are publications that support the biological activity of the product.
Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID: 28759015
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Keywords: MAIT 203, MAIT 203 supplier, MAIT203, APC, Asef, interaction, inhibitors, inhibits, colorectal, cancer, migration, Rho, 6382, Tocris Bioscience
Citations for MAIT 203
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Currently there are no citations for MAIT 203.
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