MAIT 203

Pricing Availability Delivery Time Qty
Cat.No. 6382 - MAIT 203 | Z-Ala-Gly-Glu-Ala-Cpa-Tyr-Glu-Gly-Gly-Gly-Gly-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
Description: APC-Asef interaction inhibitor

Biological Activity

Inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro.

Technical Data

M. Wt 2517.83
Formula C106H177N43O29

(Modifications: Ala-1 = Z-Ala, X-5= 3-Cyclopentyl-L-alanine, Arg-21= C-terminal amide)

Storage Store at -20°C
Smiles C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2517.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.4 mL 1.99 mL 3.97 mL
5 mM 0.08 mL 0.4 mL 0.79 mL
10 mM 0.04 mL 0.2 mL 0.4 mL
50 mM 0.01 mL 0.04 mL 0.08 mL

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Product Datasheets

Safety Datasheet


References are publications that support the biological activity of the product.

Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID: 28759015

If you know of a relevant reference for MAIT 203, please let us know.

Keywords: MAIT 203, MAIT 203 supplier, MAIT203, APC, Asef, interaction, inhibitors, inhibits, colorectal, cancer, migration, G, Proteins, (Small), 6382, Tocris Bioscience

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Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis