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MAIT 203

Cat. No. 6382 Submit a Review Datasheet / COA / SDS

Discontinued Product

MAIT 203 (Cat. No. 6382) has been withdrawn from sale for commercial reasons.
Cat.No. 6382 - MAIT 203 | Z-Ala-Gly-Glu-Ala-Cpa-Tyr-Glu-Gly-Gly-Gly-Gly-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
Description: APC-Asef (RhoGEF4) interaction inhibitor
Datasheet
Citations
Reviews
Biological Activity Technical Data Datasheets References

Biological Activity for MAIT 203

MAIT 203 is an inhibits interaction of APC and Asef (RhoGEF4). Inhibits colorectal cancer cell migration and invasion in vitro.

Technical Data for MAIT 203

M. Wt 2517.83
Formula C106H177N43O29
Sequence AGEAXYEGGGGGRKKRRQRRR

(Modifications: Ala-1 = Z-Ala, X-5= 3-Cyclopentyl-L-alanine, Arg-21= C-terminal amide)
Storage Store at -20°C
PubChem ID 132470912
InChI Key BWXFXXHBUFJJSA-YLOXEXSPSA-N
Smiles C[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1CCCC1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for MAIT 203

References are publications that support the biological activity of the product.

Jiang et al (2017) Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat.Chem.Biol. 13 994 PMID: 28759015

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Keywords: MAIT 203, MAIT 203 supplier, MAIT203, APC, Asef, interaction, inhibitors, inhibits, colorectal, cancer, migration, Rho, 6382, Tocris Bioscience

Citations for MAIT 203

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Currently there are no citations for MAIT 203.

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