Pricing Availability   Qty
Description: Fluorescent potassium ion (K+) indicator, membrane permeable
Chemical Name: Acetyloxymethyl 3-[3-(acetyloxymethoxy)-7-[3-(acetyloxymethoxy)-3-oxopropyl]-4,5-dichloro-9-[4-(5,17-dimethyl-8,14,24,27,32,35-hexaoxa-1,11,21-triazatetracyclo[,7.015,20]heptatriaconta-2(7),3,5,15(20),16,18-hexaen-11-yl)-3-(2-methoxyethoxy)phenyl]-6-oxoxanthen-2-yl]propanoate
Purity: ≥90% (HPLC)
Literature (1)

Biological Activity for IPG-4 AM

IPG-4 AM is a membrane-permeable fluorescent potassium ion (K+) indicator. It binds to potassium (Kd = 7 mM). Excitation and emission maxima (λ) are 525 and 545 nm, respectively. It has 100:1 selectivity for K+ over Na+ ions. It can be used to detect in real time changes in intracellular K+. Also used to monitor extracellular K+ changes in vivo.

It is recommended to prepare stock solutions in DMSO.

Optical Data for IPG-4 AM

λabs 525 nm
λem 545 nm
Cell Permeable Yes
Application Confocal microscopy, Flow cytometry

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Technical Data for IPG-4 AM

M. Wt 1333.27
Formula C67H79Cl2N3O21
Storage Store at -20°C
Purity ≥90% (HPLC)
PubChem ID 163342041

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for IPG-4 AM

References are publications that support the biological activity of the product.

Rana et al (2019) Calibration and characterization of intracellular Asante Potassium Green probes, APG-2 and APG-4. Anal.Biochem. 567 8 PMID: 30503709

Kikuchi et al (2022) Electrochemical potential enables dormant spores to integrate environmental signals. Science 378 43 PMID: 36201591

Humphries et al (2017) Species-independent attraction to biofilms through electrical signaling. Cell 168 200 PMID: 28086091

Hanalioglu et al (2022) Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation. J.Headache Pain 23 107 PMID: 35986251

If you know of a relevant reference for IPG-4 AM, please let us know.

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Citations for IPG-4 AM

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Literature in this Area

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

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