H3K27(Me3) (15-34)

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Cat.No. 6213 - H3K27(Me3) (15-34) | Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me3)-Ser-Ala-Pro-Ala-Thr-Gly-Gly
Description: Histone H3 peptide; substrate for methyltransferase/demethylase enzymes
Datasheet
Citations
Literature

Biological Activity

Histone peptide. Substrate for methyltransferase/demethylase enzymes. Peptide derived from human histone isotype 3.1.

Technical Data

M. Wt 2023.38
Formula C87H157N30O25
Sequence APRKQLATKAARKSAPATGG

(Modifications: Lys-13 = Lys(Me3))

Storage Store at -20°C
InChI Key SYQRIXOTDLKCAB-UWJSCCMBNA-N
Smiles [H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCC[N](C)(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)NCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2023.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.49 mL 2.47 mL 4.94 mL
5 mM 0.1 mL 0.49 mL 0.99 mL
10 mM 0.05 mL 0.25 mL 0.49 mL
50 mM 0.01 mL 0.05 mL 0.1 mL

Molarity Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Chadwick and Willard et al (2004) Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc.Natl.Acad.Sci.U.S.A. 101 17450 PMID: 15574503


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Keywords: H3K27(Me3) (15-34), supplier, histone, H3, peptide, demethylases, demethylation, methyltransferases, methylation, enzyme, substrate, Histone, Peptides, Enzyme, Substrates, /, Activators, Enzyme, Substrates, /, Activators, Tocris Bioscience

Citations for H3K27(Me3) (15-34)

Citations are publications that use Tocris products.

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