Guanidine Hydrochloride

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Cat.No. 5221 - Guanidine Hydrochloride | CH5N3.HCl | CAS No. 50-01-1
Description: Protein denaturant
Purity: ≥99%
Reviews (1)
Literature (1)

Biological Activity

Protein denaturant.

Technical Data

M. Wt 95.53
Formula CH5N3.HCl
Storage Store at RT
Purity ≥99%
CAS Number 50-01-1
PubChem ID 5742
Smiles NC(N)=N.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
water 573.18 6000

Preparing Stock Solutions

The following data is based on the product molecular weight 95.53. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
60 mM 0.17 mL 0.87 mL 1.74 mL
300 mM 0.03 mL 0.17 mL 0.35 mL
600 mM 0.02 mL 0.09 mL 0.17 mL
3000 mM 0 mL 0.02 mL 0.03 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Keywords: Guanidine Hydrochloride, Guanidine Hydrochloride supplier, protein, denaturant, Biochemicals, and, Molecular, Biology, 5221, Tocris Bioscience

Citations for Guanidine Hydrochloride

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Reviews for Guanidine Hydrochloride

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Guanidine Hydrochloride was used to decrease enzyme activity of streptomycin adenylyltransferase and increase the solubility.
By Anonymous on 12/24/2019
Species: Human

Guanidine Hydrochloride was used to decrease enzyme activity of streptomycin adenylyltransferase and increase the solubility of hydrophobic molecules. At high concentrations of guanidinium chloride (e.g., 6 M), proteins lose their ordered structure, and they tend to become randomly coiled, i.e. they do not contain any residual structure.

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Literature in this Area

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