Discontinued Product

Gatifloxacin (Cat. No. 3849) has been withdrawn from sale for commercial reasons.
Cat.No. 3849 - Gatifloxacin | C19H22FN3O4 | CAS No. 112811-59-3
Description: Antibiotic; inhibits bacterial type II topoisomerase
Alternative Names: AM 1155
Chemical Name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Purity: ≥98% (HPLC)
Reviews (1)
Literature (3)

Biological Activity for Gatifloxacin

Fluoroquinolone antibiotic. Inhibits bacterial type II topoisomerases (IC50 values are 0.109 and 13.8 μg/ml for E.coli DNA gyrase and S.aureus topoisomerase IV respectively). Displays potent activity against gram-positive and gram-negative bacteria. Stimulates short-term self-renewal in both human and mouse embryonic stem cells in vitro.

Technical Data for Gatifloxacin

M. Wt 375.39
Formula C19H22FN3O4
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 112811-59-3
PubChem ID 5379
Smiles O=C2C(C(O)=O)=CN(C3CC3)C1=C(OC)C(N4CC(C)NCC4)=C(F)C=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Gatifloxacin

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Reviews for Gatifloxacin

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Gatifloxacin was used to understand its resistance pattern against S. aureus.
By Anonymous on 02/09/2019
Species: Human

Gatifloxacin was used to understand its resistance pattern against S. aureus. E. coli strains were grown in Luria-Bertani medium, and S. aureus strains were grown in brain heart infusion medium for resistance study.

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