You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for GA3-AM
GA3-AM is a Gibberellin-analog (GA3) chemical dimerizer; induces rapid dimerization of GAIs and GID1. GA3-AM crosses the plasma membrane, is cleaved by cytosolic esterase releasing GA3, which then binds GID1- this complex then in turn forms a complex with GAI; this system works on a timescale of seconds (EC50 = 310 nM). GA3 and rapamycin (Cat. No. 1292) chemically inducible dimerization systems are orthogonal. Cell permeable.
Technical Data for GA3-AM
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for GA3-AM
References are publications that support the biological activity of the product.
Lin et al (2013) Rapidly reversible manipulation of molecular activities using dual chemical dimerizers Angew.Chem.Int.Ed.Engl. 52 6450 PMID: 23649661
Miyamoto et al (2012) Rapid and orthogonal logic gating with a gibberellin-induced dimerization system Nat.Chem.Biol. 8 465 PMID: 22446836
Keywords: GA3-AM, GA3-AM supplier, Chemical, dimerizer, cell, permeable, chemically, inducible, dimerization, system, Biochemicals, and, Molecular, Biology, Protein, Dimerizers, 5407, Tocris Bioscience
2 Citations for GA3-AM
Citations are publications that use Tocris products. Selected citations for GA3-AM include:
Xi et al (2022) Passage number affects differentiation of sensory neurons from human induced pluripotent stem cells. Sci Rep 12 15869 PMID: 36151116
Yong Chul et al (2019) 5-HT2A receptor activation enhances NMDA receptor-mediated glutamate responses through Src kinase in the dendrites of rat jaw-closing motoneurons. J Physiol 597 2565-2589 PMID: 30919966
Reviews for GA3-AM
There are currently no reviews for this product. Be the first to review GA3-AM and earn rewards!
Have you used GA3-AM?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image