FH 1

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Cat.No. 5254 - FH 1 | C17H18N2O2 | CAS No. 2719-05-3
Description: Enhances iPSC-derived hepatocyte differentiation and maturation
Alternative Names: NSC 12407, BRD-K4477
Chemical Name: N,N'-(Methylenedi-4,1-phenylene)bis-acetamide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Enhances differentiation of induced pluripotent stem cells (iPSCs) to hepatocytes; also promotes the maturation of iPSC-derived hepatocytes.

Compound Libraries

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Technical Data

M. Wt 282.34
Formula C17H18N2O2
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 2719-05-3
PubChem ID 94990
InChI Key OEXMNSOPAKOPEF-UHFFFAOYSA-N
Smiles CC(NC1=CC=C(CC2=CC=C(NC(C)=O)C=C2)C=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.23 100

Preparing Stock Solutions

The following data is based on the product molecular weight 282.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.54 mL 17.71 mL 35.42 mL
5 mM 0.71 mL 3.54 mL 7.08 mL
10 mM 0.35 mL 1.77 mL 3.54 mL
50 mM 0.07 mL 0.35 mL 0.71 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Shan et al (2013) Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat.Chem.Biol. 9 514 PMID: 23728495


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Citations for FH 1

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