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Description: Chelating agent
Alternative Names: Ethylenediaminetetraacetic acid
Chemical Name: N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine
Biological Activity
Chelating agent; sequesters di- and trivalent metal ions.
Technical Data
| M. Wt | 292.24 |
| Formula | C10H16N2O8 |
| Storage | Store at RT |
| CAS Number | 60-00-4 |
| PubChem ID | 6049 |
| InChI Key | KCXVZYZYPLLWCC-UHFFFAOYSA-N |
| Smiles | O=C(CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets
References
References are publications that support the biological activity of the product.
Tandogan and Ulusu (2007) The inhibition kinetics of yeast glutathione reductase by some metal ions. J.Enz.Inhib.Med.Chem. 22 489
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Keywords: EDTA, EDTA supplier, Chelating, agent, Reagents, Ethylenediaminetetraacetic, acid, Biochemicals, and, Molecular, Biology, 2811, Tocris Bioscience
1 Citation for EDTA
Citations are publications that use Tocris products. Selected citations for EDTA include:
Höfner et al (2015) Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin. Cardiovasc Res 4 503 PMID: 25702639
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Reviews for EDTA
Average Rating: 5 (Based on 1 Review.)
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EDTA inhibits 15d-PGJ2 induced TNFa production by cardiomyocytes.
By
Anonymous on 12/10/2018
Assay Type: In Vitro
Species: Mouse
Cell Line/Tissue: Cardiomyocytes
HL-1 cells were incubated with EDTA (5 mM) for 30 min prior to 15d-PGJ2 (15 µM) treatment for 4 h to follow TNFa concentrations in the cell culture medium. Addition of EDTA resulted in abolition of 15d-PGJ2 induced TNFa production.
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