Potent mTOR inhibitor (IC50 = 15 nM). Exhibits >60-fold selectivity for mTOR over PI 3-kinases and is inactive against a panel of other kinases. Inhibits growth of ER-positive MCF7 breast cancer cells in vitro (EC50 = 8.5 nM). Cell permeable.
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of eCF 309 is reviewed on the Chemical Probes website.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 383.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.61 mL||13.04 mL||26.08 mL|
|5 mM||0.52 mL||2.61 mL||5.22 mL|
|10 mM||0.26 mL||1.3 mL||2.61 mL|
|50 mM||0.05 mL||0.26 mL||0.52 mL|
References are publications that support the products' biological activity.
If you know of a relevant reference for eCF 309, please let us know.
View Related Products by Product Action
Keywords: eCF 309, supplier, eCF309, mTOR, inhibitors, inhibits, potent, anticancer, mTOR, mTOR, Tocris Bioscience
Citations for eCF 309
Citations are publications that use Tocris products.
Currently there are no citations for eCF 309. Do you know of a great paper that uses eCF 309 from Tocris? If so please let us know.
Reviews for eCF 309
There are currently no reviews for this product. Be the first to review eCF 309 and earn rewards!
Have you used eCF 309?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.