D2 receptor antagonist. Also exhibits affinity for 5-HT, α-adrenergic and histamine receptors,and hERG channels. Antipsychotic and antiemetic.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 379.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.64 mL||13.18 mL||26.36 mL|
|5 mM||0.53 mL||2.64 mL||5.27 mL|
|10 mM||0.26 mL||1.32 mL||2.64 mL|
|50 mM||0.05 mL||0.26 mL||0.53 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Peroutka and Synder (1980) Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency. Am.J.Psychiatry 137 1518 PMID: 6108081
Rajamani et al (2005) A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorg.Med.Chem.Lett. 15 1737 PMID: 15745831
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Keywords: dopamine receptors D2 antagonists antipsychotics antiemetics herg channels D2 Receptors
Citations for Droperidol
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Literature in this Area
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