Dopamine Receptors Scientific Review

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Dopamine Receptors Scientific Review

Phillip G. Strange & Kim Neve

Review excerpt: "It was not until the late 1950's that dopamine was recognized as a neurotransmitter in its own right, but the demonstration of its non-uniform distribution in the brain, distinct from the distribution of noradrenaline, suggested a specific functional role for dopamine. Interest in dopamine was intensified by the realization that dopamine had an important role in the pathogenesis or drug treatment of certain neurological disorders, e.g. Parkinson's disease and schizophrenia. This lead to much research on the sites of action of dopamine and the dopamine receptors."