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Biological Activity for CW 008
CW 008 is a cAMP/PKA/CREB pathway activator. Promotes osteogenic differentiation of human bone marrow-derived MSCs in vitro. Increases bone mass and bone volume density in ovariectomized mice.
Compound Libraries for CW 008
Technical Data for CW 008
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CW 008
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CW 008
The following data is based on the product molecular weight 420.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.5 mM||4.76 mL||23.79 mL||47.58 mL|
|2.5 mM||0.95 mL||4.76 mL||9.52 mL|
|5 mM||0.48 mL||2.38 mL||4.76 mL|
|25 mM||0.1 mL||0.48 mL||0.95 mL|
References for CW 008
References are publications that support the biological activity of the product.
Kim et al (2013) An activator of the cAMP/PKA/CREB pathway promotes osteogenesis from human mesenchymal stem cells. J.Cell.Physiol. 228 617 PMID: 22886506
If you know of a relevant reference for CW 008, please let us know.
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Keywords: CW 008, CW 008 supplier, CW008, MSC, mesenchymal, stem, cells, protein, kinase, A, PKA, activators, CREB, cAMP, osteogenic, osteogenesis, activates, Protein, Kinase, Osteogenic, Stem, Cells, 5495, Tocris Bioscience
Citations for CW 008
Citations are publications that use Tocris products.
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Reviews for CW 008
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Literature in this Area
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