You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Near-infrared probe that binds to Aβ40 aggregates (Kd = 38 nM) and elicits an emission blue shift. Shown to bind to plaques in APP-PS1 transgenic mice, in vitro. Detects senile plaques in 19-month-old Tg2576 mice in vivo. Penetrates the blood-brain barrier.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||2.05||5 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 410.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.05 mM||48.75 mL||243.75 mL||487.5 mL|
|0.25 mM||9.75 mL||48.75 mL||97.5 mL|
|0.5 mM||4.87 mL||24.37 mL||48.75 mL|
|2.5 mM||0.97 mL||4.87 mL||9.75 mL|
References are publications that support the biological activity of the product.
Ran et al (2009) Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J.Am.Chem.Soc. 131 15257 PMID: 19807070
Ran et al (2011) Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 6 e19362 PMID: 21559413
If you know of a relevant reference for CRANAD 2, please let us know.
View Related Products by Target
Keywords: CRANAD 2, CRANAD 2 supplier, near-infrared, NIR, probes, AB40, AB, amyloid-beta, beta-amyloid, aggregates, senile, plaques, Tg2576, amyloidb, amyloidβ, Amyloid, Beta, Peptides, Other, Fluorescent, Probes, B, 4803, Tocris Bioscience
Citations for CRANAD 2
Citations are publications that use Tocris products.
Currently there are no citations for CRANAD 2. Do you know of a great paper that uses CRANAD 2 from Tocris? Please let us know.
Reviews for CRANAD 2
There are currently no reviews for this product. Be the first to review CRANAD 2 and earn rewards!
Have you used CRANAD 2?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide [Spring/Summer 2019]
Our new product guide highlights over 215 new products added to the Tocris Bioscience range during the first half of 2019.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells