Cinanserin hydrochloride

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Cat.No. 0460 - Cinanserin hydrochloride | C20H24N2OS.HCl | CAS No. 54-84-2
Description: Selective 5-HT2 antagonist
Chemical Name: N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide hydrochloride
Purity: ≥99% (HPLC)
Datasheet
Citations (1)
Literature

Biological Activity

5-HT2 antagonist.

Technical Data

M. Wt 376.94
Formula C20H24N2OS.HCl
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 54-84-2
PubChem ID 6433141
InChI Key LXGJPDKYMJJWRB-IERUDJENSA-N
Smiles O=C(/C=C/C2=CC=CC=C2)NC1=CC=CC=C1SCCCN(C)C.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 50 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 376.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.26 mL 26.53 mL
5 mM 0.53 mL 2.65 mL 5.31 mL
10 mM 0.27 mL 1.33 mL 2.65 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Leysen et al (1981) Receptor binding profile of R-41-468, a novel antagonist at 5HT2 receptors. Life Sci. 28 1015 PMID: 6261070

Pierce et al (1992) Molecular structure basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors. Naunyn Schmiedebergs Arch.Pharmacol. 346 4 PMID: 1407003


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Keywords: Cinanserin hydrochloride, supplier, Selective, 5-HT2, antagonists, Non-Selective, Serotonin, Receptors, Non-selective, 5-HT2, Tocris Bioscience

1 Citation for Cinanserin hydrochloride

Citations are publications that use Tocris products. Selected citations for Cinanserin hydrochloride include:

Buznikov et al (2010) A putative 'pre-nervous' endocannabinoid system in early echinoderm development. Dev Neurosci 32 1 PMID: 19907129


Do you know of a great paper that uses Cinanserin hydrochloride from Tocris? If so please let us know.

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Literature in this Area

GPCR

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling
5-HT Receptors

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Pathways for Cinanserin hydrochloride

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