Antivirals

Antivirals are drugs that inhibit viral infection, targeting virus entry, assembly or replication. Mechanisms of antiviral action include blocking virus replication at key points, such as interfering with DNA polymerization or protease inhibition. They are used to treat viral infections such as HIV and CMV.

Products
Literature (2)
Cat. No. Product Name / Activity
5612 18A
HIV cell entry blocker
4148 Abacavir hemisulfate
Reverse transcriptase inhibitor; antiretroviral
5852 Acetyl Pepstatin
Aspartic protease inhibitor; inhibits HIV-1/2 proteinases
2513 Acyclovir
Antiviral agent; active against herpes simplex viruses
2404 Ambroxol hydrochloride
Inhibits influenza (H3N2) viral replication
5736 Aphidicolin
Antiviral; inhibits DNA polymerase α, δ and ε
2151 API-2
Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
1777 Arctigenin
Potent MEK1 inhibitor; antiproliferative and antiviral agent
2457 Arcyriaflavin A
Inhibits HCMV; potent cdk4 inhibitor; also potently inhibits CaM kinase II
4150 Azidothymidine
Selective reverse transcriptase inhibitor; antiretroviral
2711 Bay 55-9837
VPAC2 agonist; reduces HIV-1 viral replication
6246 BF 738735
Broad spectrum enterovirus replication inhibitor; PI 4-kinase IIIβ inhibitor
5009 BMS 509744
ITK kinase inhibitor; attenuates establishment of HIV infection
6974 BMS 986094
Prodrug of HCV RNA polymerase inhibitor 2'-C-methyl guanosine triphosphate; potent HCV replication inhibitor
2743 Caffeic acid phenethyl ester
Inhibitor of NFκB activation; antiviral agent
3193 Camostat mesylate
Orally active protease inhibitor; inhibits entry of SARS-Cov-2 into lung cells
6258 CC 401 dihydrochloride
Inhibitor of HCMV replication; also high affinity JNK inhibitor
0460 Cinanserin hydrochloride
Inhibits replication of SARS-CoV; 3C-like proteinase inhibitor and 5HT2 antagonist
2483 Costunolide
Telomerase inhibitor; displays antiviral properties
1437 D609
Phosphatidyl choline-specific phospholipase C inhibitor; antitumor and antiviral agent
2423 DAPTA
CCR5 antagonist; selective antiviral for R5 tropic HIV-1 strains
6710 Darunavir
Highly potent HIV protease inhibitor
1770 Deguelin
Anticancer and antiviral agent; pro-apoptotic
4149 Delavirdine mesylate
Non-nucleoside reverse transcriptase inhibitor
5601 DMXAA
mSTING agonist; antiviral
4545 E 64d
Cathepsin inhibitor; inhibits entry of SARS-Cov-2 into cells in combination with Camostat mesylate (Cat. No. 3193)
6234 Entecavir
Potent and selective hepatitis B virus inhibitor
7225 Favipiravir
Viral RNA polymerase inhibitor; antiviral
4320 FC 131
CXCR4 antagonist; displays anti-HIV activity
6494 Galangin
Broad spectrum antiviral; induces autophagy and inhibits TRPC5
7227 GS 441524
Viral RNA-dependent RNA polymerase inhibitor; broad spectrum antiviral nucelotide
3988 Hesperadin hydrochloride
Displays broad spectrum antiviral activity against influenza viruses
6994 HODHBt
STAT5-SUMO protein-protein interaction inhibitor
1416 Homoharringtonine
Inhibits SARS-CoV-2 infection in vitro
5741 25-Hydroxycholesterol
Antiviral; also α-crystallin (cryAB) chaperone
1520 Hypericin
Photosensitive antiviral, anticancer and antidepressant agent
3700 Imiquimod
Immunomodulator; has antiviral and antitumor activity
4596 IT1t dihydrochloride
Potent CXCR4 antagonist; blocks interaction with the HIV envelope protein
2287 K-252c
PKC inhibitor; antiviral against strains of human cytomegalovirus
6126 KRH 3955 hydrochloride
Inhibits HIV-1 replication; potent CXCR4 antagonist
2307 Leukotriene B4
Lipid inflammatory mediator; antiviral towards DNA viruses and retroviruses
7052 Lopinavir
Highly potent and selective HIV-1 protease inhibitor
3756 Maraviroc
Selective CCR5 antagonist; inhibits HIV-1 cell entry
5604 MI 14
Potent and selective PI 4-kinase IIIβ inhibitor
3117 Miglustat hydrochloride
Glycosyltransferase inhibitor; broad spectrum antiviral activity
1505 Mycophenolic acid
Inosine monophosphate dehydrogenase inhibitor; antiviral and antitumor
5811 NBD 556
CD4 mimetic; blocks HIV-1 cell entry
3766 Nelfinavir mesylate
Potent HIV-1 protease inhibitor
6339 Netilmicin sulfate
Inhibits HIV-1 replication; also semisynthetic aminoglycoside antibiotic
6652 NGI 1
Oligosaccharyltransferase (OST) inhibitor; anti-flaviviral
6045 NITD 008
Antiviral; selective flavivirus inhibitor
6244 OG-L002
Suppresses herpes simplex infection in vivo; also LSD1 inhibitor.
4611 PBP 10
Antiviral and FPR2 inhibitor; inhibits influenza viruses
3354 PF 429242 dihydrochloride
Competitive inhibitor of SREBP site 1 protease; antiviral
4107 Probenecid
Inhibits influenza A infection in vitro and in vivo; MRP and OAT3 inhibitor
7226 Remdesivir
Viral RNA-dependent RNA polymerase inhibitor; broad spectrum antiviral nucelotide prodrug
4536 Resiquimod
Toll-like receptor 7 (TLR7) agonist; antiviral
4501 Ribavirin
Antiviral guanosine analog; blocks eIF4E activity
5856 Ritonavir
HIV-1 and HIV-2 protease inhibitor
5389 Ro 48-8071 fumarate
Inhibits Ebola virus (EBOV) cell entry; OSC inhibitor
4694 Ro 5-3335
Core binding factor inhibitor; inhibits HIV-1 replication
0630 Rosmarinic acid
Anti-inflammatory, cytostatic and antiviral; GPR35 agonist
6414 Rupintrivir
Potent and selective irreversible human rhinovirus 3C protease inhibitor
4418 Saquinavir mesylate
HIV protease inhibitor
7233 SBP1
Binds SARS-CoV-2 spike protein receptor binding domain
1410 SDM25N hydrochloride
Inhibits dengue virus replication; also potent, selective non-peptide δ antagonist
6829 (R)-Shikonin
Attenuates HIV-1 replication; induces necroptosis; anti-inflammatory
4990 Stavudine
Nucleoside analog; antiviral
6658 Telaprevir
Hepatitis C virus (HCV) protease NS3/4A inhibitor
3666 Tenofovir
Selectively inhibits HIV reverse transcriptase
3356 WR 1065 dihydrochloride
p53 activator; exhibits broad spectrum antiviral activity

Literature for Antivirals

Tocris offers the following scientific literature for Antivirals to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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