You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for CE3F4
CE3F4 is a noncompetitive Epac1 inhibitor. Blocks Epac-induced Rap activation and prevents isoprenaline-induced autophagy flux in cardiomyocytes. Has no effect on PKA activity in the presence of cAMP.
Compound Libraries for CE3F4
Technical Data for CE3F4
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for CE3F4
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for CE3F4
The following data is based on the product molecular weight 351.01. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.85 mL||14.24 mL||28.49 mL|
|5 mM||0.57 mL||2.85 mL||5.7 mL|
|10 mM||0.28 mL||1.42 mL||2.85 mL|
|50 mM||0.06 mL||0.28 mL||0.57 mL|
References for CE3F4
References are publications that support the biological activity of the product.
Laurent et al (2015) Exchange protein directly activated by cAMP 1 promotes autophagy during cardiomyocyte hypertrophy. Cardiovasc.Res. 105 55 PMID: 25411381
Courilleau et al (2012) Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac. J.Biol.Chem. 287 44192 PMID: 23139415
If you know of a relevant reference for CE3F4, please let us know.
View Related Products by Product Action
Keywords: CE3F4, CE3F4 supplier, noncompetitive, Epac1, inhibitors, inhibits, autophagy, Exchange, proteins, Rap, guanine, nucleotide, exchange, factor, 3, RAPGEF3, cAMP, GEFI, EPAC, 4793, Tocris Bioscience
1 Citation for CE3F4
Citations are publications that use Tocris products. Selected citations for CE3F4 include:
Jakobsen et al (2019) Soluble adenylyl cyclase-mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function. J Neurosci Res 97 1018 PMID: 31172581
Do you know of a great paper that uses CE3F4 from Tocris? Please let us know.
Reviews for CE3F4
There are currently no reviews for this product. Be the first to review CE3F4 and earn rewards!
Have you used CE3F4?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image