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C-Laurdan is a fluorescent probe for imaging lipid rafts. Used to detect membrane polarity via one and two-photon fluorecence imaging. Two photon excitation spectra = 780 nm; one photon absorption/emission spectra = 348/423 nm; Quantum yield = 0.43.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 397.56. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.52 mL||12.58 mL||25.15 mL|
|5 mM||0.5 mL||2.52 mL||5.03 mL|
|10 mM||0.25 mL||1.26 mL||2.52 mL|
|50 mM||0.05 mL||0.25 mL||0.5 mL|
References are publications that support the biological activity of the product.
Kim et al (2007) A two-photon fluorescent probe for lipid raft imaging: C-laurdan. Chembiochem 8 553 PMID: 17300111
Barucha-Kraszewska et al (2013) Will C-Laurdan dethrone Laurdan in fluorescent solvent relaxation techniques for lipid membrane studies? Langmuir 29 1174 PMID: 23311388
Mazeres et al (2014) Characterization of M-laurdan, a versatile probe to explore order in lipid membranes. F1000Res. 3 172 PMID: 25485094
If you know of a relevant reference for C-Laurdan, please let us know.
Keywords: C-Laurdan, C-Laurdan supplier, fluorescent, probe, imaging, lipid, rafts, membrane, polarity, two-photon, 2-photon, one-photon, 1-photon, Fluorescent, Lipid, Probes, and, Cell, Membrane, Stains, 7273, Tocris Bioscience
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