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Description: Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays
Alternative Names: 6-Biotin-17-NAD
Chemical Name: β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide sodium salt
Purity: ≥95% (HPLC)

Biological Activity for Biotin-LC-NAD+

Biotin-LC-NAD+ is a biotinylated analog of β-NAD+. Commonly used reagent in LSD1 and PARP1 assays.

Technical Data for Biotin-LC-NAD+

M. Wt 1181.09
Formula C45H67N12NaO18P2S
Storage Store at -80°C
Purity ≥95% (HPLC)
PubChem ID 134160253
Smiles [H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(NCCCCCC(NCCCCCC(NCCNC3=C4N=CN(C4=NC=N3)[C@@H]5O[C@@H]([C@H]([C@H]5O)O)COP([O-])(OP([O-])(OC[C@H]6O[C@@H]([N+]7=CC=CC(C(N)=O)=C7)[C@@H]([C@@H]6O)O)=O)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Biotin-LC-NAD+

Solvent Max Conc. mg/mL Max Conc. mM
water 11.81 10

Preparing Stock Solutions for Biotin-LC-NAD+

The following data is based on the product molecular weight 1181.09. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.47 mL 42.33 mL 84.67 mL
0.5 mM 1.69 mL 8.47 mL 16.93 mL
1 mM 0.85 mL 4.23 mL 8.47 mL
5 mM 0.17 mL 0.85 mL 1.69 mL

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Product Datasheets for Biotin-LC-NAD+

Certificate of Analysis / Product Datasheet
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References for Biotin-LC-NAD+

References are publications that support the biological activity of the product.

Dancy et al (2012) Azalysine analogues as probes for protein lysine deacetylation and demethylation. J.Am.Chem.Soc. 134 5138 PMID: 22352831

If you know of a relevant reference for Biotin-LC-NAD+, please let us know.

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Keywords: Biotin-LC-NAD+, Biotin-LC-NAD+ supplier, Biotinylated, analogues, beta-NAD+, β-NAD+, buffers, LSD1, PARP1, analogs, 6-Biotin-17-NAD, Biochemicals, and, Molecular, Biology, 6572, Tocris Bioscience

Citations for Biotin-LC-NAD+

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