Bax inhibitor peptide P5

Discontinued Product

Bax inhibitor peptide P5 (Cat. No. 1786) has been withdrawn from sale for commercial reasons.
Description: Inhibitor of Bax-mediated apoptosis
Citations (1)
Literature (2)
Pathways (1)

Biological Activity for Bax inhibitor peptide P5

Originally reported to be a cell-permeable synthetic peptide inhibitor of Bax that blocks apoptosis. Also available: Bax inhibitor peptide V5 (Cat. No. 1785) and Negative control (Cat. No. 1787).

Licensing Information

Sold under license

Technical Data for Bax inhibitor peptide P5

M. Wt 616.77
Formula C27H48N6O8S
Sequence PMLKE
Storage Desiccate at -20°C
CAS Number 579492-83-4
Smiles [H]N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Bax inhibitor peptide P5

Certificate of Analysis / Product Datasheet
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References for Bax inhibitor peptide P5

References are publications that support the biological activity of the product.

Sawada et al (2003) Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70. Nat.Cell.Biol. 5 352 PMID: 12652309

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Keywords: Bax inhibitor peptide P5, Bax inhibitor peptide P5 supplier, inhibitors, inhibits, Bax-mediated, apoptosis, Bcl-XL, Mcl-1, Bcl-2, Family, Bax, inhibitor, peptideP5, 1786, Tocris Bioscience

1 Citation for Bax inhibitor peptide P5

Citations are publications that use Tocris products. Selected citations for Bax inhibitor peptide P5 include:

Sanchez-Niño et al (2010) BASP1 promotes apoptosis in diabetic nephropathy. J Am Soc Nephrol 21 610 PMID: 20110383

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

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Programmed Cell Death Poster

Programmed Cell Death Poster

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

Pathways for Bax inhibitor peptide P5

Apoptosis Signaling Pathway

Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.