Cat. No. | Product Name / Activity |
---|---|
6409 | A 1210477 |
Selective, high affinity Mcl-1 inhibitor; proapoptotic | |
6960 | ABT 199 |
Selective, high affinity Bcl-2 inhibitor; orally bioavailable | |
7680 | ABT 263 New |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor | |
6835 | ABT 737 |
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines | |
4676 | ARRY 520 trifluoroacetate |
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation | |
2160 | Bax channel blocker |
Allosteric inhibitor of Bax channel activation | |
6323 | FX 1 |
Bcl-6 inhibitor; 10-fold more potent than endogenous Bcl-6 corepressors | |
3590 | Gambogic acid |
Apoptosis inducer. Inhibits Bcl-2 family proteins | |
3794 | iMAC2 |
Inhibitor of Bid-induced Bax cytochrome c release | |
4819 | Methylprednisolone |
Anti-apoptotic; upregulates expression of Bcl-xL after injury | |
5733 | ML 311 |
Inhibits Mcl-1-BIM interaction | |
6539 | Obatoclax mesylate |
Inhibitor of Bcl-2 family members; antiapoptotic |