Bax inhibitor peptide, negative control

Discontinued Product

Bax inhibitor peptide, negative control (Cat. No. 1787) has been withdrawn from sale for commercial reasons.
Description: Negative control peptide for Bax inhibitor peptide V5 (Cat. No. 1785)
Citations (1)
Literature (2)
Pathways (1)

Biological Activity

Negative control peptide for the Bax inhibitor peptide V5, which inhibits Bax translocation to mitochondria and Bax-mediated apoptosis in vitro.

Active Analog V5 also available.

Technical Data

M. Wt 600.82
Formula C28H52N6O6S
Sequence IPMIK
Storage Desiccate at -20°C
CAS Number 1315378-74-5
PubChem ID 24985487
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the biological activity of the product.

Yoshida et al (2004) Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 321 961 PMID: 15358121

Sawatzky et al (2006) The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 168 33 PMID: 16400007

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Keywords: Bax inhibitor peptide, negative control, Bax inhibitor peptide, negative control supplier, Negative, control, peptide, 5, 1786, Bax, Bcl-XL, Mcl-1, Bcl-2, Family, 1787, Tocris Bioscience

1 Citation for Bax inhibitor peptide, negative control

Citations are publications that use Tocris products. Selected citations for Bax inhibitor peptide, negative control include:

Lee et al (2010) Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells. J Cell Sci 123 1634 PMID: 20406888

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Parkinson's Disease Poster

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Programmed Cell Death Poster

Programmed Cell Death Poster

There are two currently recognized forms of programmed cell death: apoptosis and necroptosis. This poster summarizes the signaling pathways involved in apoptosis, necroptosis and cell survival following death receptor activation, and highlights the influence of the molecular switch, cFLIP, on cell fate.

Pathways for Bax inhibitor peptide, negative control

Apoptosis Signaling Pathway

Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.