Bax inhibitor peptide, negative control

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Cat.No. 1787 - Bax inhibitor peptide, negative control | Ile-Pro-Met-Ile-Lys | CAS No. 1315378-74-5
Description: Negative control peptide for Bax inhibitor peptide V5 (Cat. No. 1785)
Datasheet
Citations (1)
Literature
Pathways

Biological Activity

Negative control peptide for the Bax inhibitor peptide V5 (Cat. No. 1785), which inhibit Bax translocation to mitochondria and Bax-mediated apoptosis in vitro.

Technical Data

M. Wt 600.82
Formula C28H52N6O6S
Sequence IPMIK
Storage Desiccate at -20°C
CAS Number 1315378-74-5
PubChem ID 24985487
InChI Key VRWAAYKVABJBAQ-FQJIPJFPSA-N
Smiles [H]N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 600.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.66 mL 8.32 mL 16.64 mL
5 mM 0.33 mL 1.66 mL 3.33 mL
10 mM 0.17 mL 0.83 mL 1.66 mL
50 mM 0.03 mL 0.17 mL 0.33 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Yoshida et al (2004) Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 321 961 PMID: 15358121

Sawatzky et al (2006) The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 168 33 PMID: 16400007


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1 Citation for Bax inhibitor peptide, negative control

Citations are publications that use Tocris products. Selected citations for Bax inhibitor peptide, negative control include:

Lee et al (2010) Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells. J Cell Sci 123 1634 PMID: 20406888


Do you know of a great paper that uses Bax inhibitor peptide, negative control from Tocris? If so please let us know.

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Reviews

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Literature in this Area

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Programmed Cell Death Poster

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Pathways for Bax inhibitor peptide, negative control

Apoptosis

Apoptosis Signaling Pathway

Apoptosis is a physiological process for cell death that is critical during aging and development. It may also be referred to as cell 'suicide'. Apoptosis can be triggered by events both inside and outside of the cell.

Protocols

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