4-Ethynyl-N-ethyl-1,8-naphthalimide

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Description: Click-reactive fluorescent dye
Chemical Name: 2-Ethyl-6-ethynyl-1H-benz[de]isoquinoline
Purity: ≥98% (HPLC)
Datasheet
Citations
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Literature (1)

Biological Activity for 4-Ethynyl-N-ethyl-1,8-naphthalimide

4-Ethynyl-N-ethyl-1,8-naphthalimide is a click-activated fluorescent probe. Enables imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.

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Technical Data for 4-Ethynyl-N-ethyl-1,8-naphthalimide

M. Wt 249.26
Formula C16H11NO2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 912921-26-7
PubChem ID 25073575
InChI Key AYGXEBXIFZUSPD-UHFFFAOYSA-N
Smiles CCN(C3=O)C(C2=CC=CC1=C(C#C)C=CC3=C12)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 4-Ethynyl-N-ethyl-1,8-naphthalimide

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.49 10 with gentle warming

Preparing Stock Solutions for 4-Ethynyl-N-ethyl-1,8-naphthalimide

The following data is based on the product molecular weight 249.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.12 mL 200.59 mL 401.19 mL
0.5 mM 8.02 mL 40.12 mL 80.24 mL
1 mM 4.01 mL 20.06 mL 40.12 mL
5 mM 0.8 mL 4.01 mL 8.02 mL

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Product Datasheets for 4-Ethynyl-N-ethyl-1,8-naphthalimide

References for 4-Ethynyl-N-ethyl-1,8-naphthalimide

References are publications that support the biological activity of the product.

Yuan et al (2014) Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium. Synth.Commun. 44 1007

Sawa et al (2006) Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc.Natl.Acad.Sci.U.S.A. 103 12371 PMID: 16895981


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Keywords: 4-Ethynyl-N-ethyl-1,8-naphthalimide, 4-Ethynyl-N-ethyl-1,8-naphthalimide supplier, fluorescent, probes, fucose, fucosylation, fusoylated, glycoproteins, glycolipids, click, activated, imaging, Click-Reactive, Fluorescent, Dyes, 5712, Tocris Bioscience

Citations for 4-Ethynyl-N-ethyl-1,8-naphthalimide

Citations are publications that use Tocris products.

Currently there are no citations for 4-Ethynyl-N-ethyl-1,8-naphthalimide. Do you know of a great paper that uses 4-Ethynyl-N-ethyl-1,8-naphthalimide from Tocris? Please let us know.

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Literature in this Area

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Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

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