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Submit Review4-Ethynyl-N-ethyl-1,8-naphthalimide is a click-activated fluorescent probe. Enables imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.
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Spectral ViewerM. Wt | 249.26 |
Formula | C16H11NO2 |
Storage | Store at -20°C |
Purity | ≥98% (HPLC) |
CAS Number | 912921-26-7 |
PubChem ID | 25073575 |
InChI Key | AYGXEBXIFZUSPD-UHFFFAOYSA-N |
Smiles | CCN(C3=O)C(C2=CC=CC1=C(C#C)C=CC3=C12)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 2.49 | 10 with gentle warming |
The following data is based on the product molecular weight 249.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 40.12 mL | 200.59 mL | 401.19 mL |
0.5 mM | 8.02 mL | 40.12 mL | 80.24 mL |
1 mM | 4.01 mL | 20.06 mL | 40.12 mL |
5 mM | 0.8 mL | 4.01 mL | 8.02 mL |
References are publications that support the biological activity of the product.
Yuan et al (2014) Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium. Synth.Commun. 44 1007
Sawa et al (2006) Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc.Natl.Acad.Sci.U.S.A. 103 12371 PMID: 16895981
If you know of a relevant reference for 4-Ethynyl-N-ethyl-1,8-naphthalimide, please let us know.
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Citations are publications that use Tocris products.
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