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Cat.No. 5712 - 4-ethynyl-N-ethyl-1,8-naphthalimide | C16H11NO2 | CAS No. 912921-26-7
Description: Click-activated fluorescent probe
Chemical Name: 2-Ethyl-6-ethynyl-1H-benz[de]isoquinoline
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity

Click-activated fluorescent probe. Enables imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.

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Technical Data

M. Wt 249.26
Formula C16H11NO2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 912921-26-7
PubChem ID 25073575
Smiles CCN(C3=O)C(C2=CC=CC1=C(C#C)C=CC3=C12)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 2.49 10 with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 249.26. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.12 mL 200.59 mL 401.19 mL
0.5 mM 8.02 mL 40.12 mL 80.24 mL
1 mM 4.01 mL 20.06 mL 40.12 mL
5 mM 0.8 mL 4.01 mL 8.02 mL

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References are publications that support the biological activity of the product.

Yuan et al (2014) Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium. Synth.Commun. 44 1007

Sawa et al (2006) Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc.Natl.Acad.Sci.U.S.A. 103 12371 PMID: 16895981

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Citations for 4-ethynyl-N-ethyl-1,8-naphthalimide

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