4-ethynyl-N-ethyl-1,8-naphthalimide

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Cat.No. 5712 - 4-ethynyl-N-ethyl-1,8-naphthalimide | C16H11NO2 | CAS No. 912921-26-7
Description: Click-activated fluorescent probe
Chemical Name: 2-Ethyl-6-ethynyl-1H-benz[de]isoquinoline
Purity: ≥98% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Click-activated fluorescent probe. Enables imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.

Technical Data

M. Wt 249.26
Formula C16H11NO2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 912921-26-7
PubChem ID 25073575
InChI Key AYGXEBXIFZUSPD-UHFFFAOYSA-N
Smiles CCN(C3=O)C(C2=CC=CC1=C(C#C)C=CC3=C12)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 2.49 10mM with gentle warming

Preparing Stock Solutions

The following data is based on the product molecular weight 249.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.01 mL 20.06 mL 40.12 mL
5 mM 0.8 mL 4.01 mL 8.02 mL
10 mM 0.4 mL 2.01 mL 4.01 mL
50 mM 0.08 mL 0.4 mL 0.8 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Yuan et al (2014) Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium. Synth.Commun. 44 1007 PMID:

Sawa et al (2006) Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo. Proc.Natl.Acad.Sci.U.S.A. 103 12371 PMID: 16895981


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Citations for 4-ethynyl-N-ethyl-1,8-naphthalimide

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