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Cat.No. 4815 - 3-Cyano-7-ethoxycoumarin | C12H9NO3 | CAS No. 117620-77-6
Description: Fluorescent cytochrome P450 substrate
Chemical Name: 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile
Purity: ≥98% (HPLC)
Literature (1)

Biological Activity

Fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.

Technical Data

M. Wt 215.2
Formula C12H9NO3
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 117620-77-6
PubChem ID 164045
Smiles O=C2C(C#N)=CC1=CC=C(OCC)C=C1O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solubility Soluble to 50 mM in DMSO


References are publications that support the biological activity of the product.

White et al (1988) A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal.Biochem. 172 304 PMID: 3189781

Donato et al (2004) Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab.Dispos. 32 699 PMID: 15205384

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Keywords: 3-Cyano-7-ethoxycoumarin, 3-Cyano-7-ethoxycoumarin supplier, CEC, Cytochrome, P450, CYP450, CYP2A1, substrates, fluorescent, probes, 4815, Tocris Bioscience

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