Fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solubility||Soluble to 50 mM in DMSO|
References are publications that support the biological activity of the product.
White et al (1988) A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal.Biochem. 172 304 PMID: 3189781
Donato et al (2004) Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab.Dispos. 32 699 PMID: 15205384
If you know of a relevant reference for 3-Cyano-7-ethoxycoumarin, please let us know.
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Keywords: 3-Cyano-7-ethoxycoumarin, 3-Cyano-7-ethoxycoumarin supplier, CEC, Cytochrome, P450, CYP450, CYP2A1, substrates, fluorescent, probes, 4815, Tocris Bioscience
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