Discontinued Product

2B-(SP) (Cat. No. 1802) has been withdrawn from sale for commercial reasons.
Description: Selective GSK-3 phosphopeptide substrate

Biological Activity for 2B-(SP)

2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3); derived from the phosphorylation site of the translation factor eIF2B.

Technical Data for 2B-(SP)

M. Wt 1835.88
Formula C71H123N26O29P

(Modifications: Ser-13 = pSer)

Storage Desiccate at -20°C
CAS Number 186901-17-7
PubChem ID 90488714
Smiles [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](COP(O)(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for 2B-(SP)

References are publications that support the biological activity of the product.

Welsh et al (1997) Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal.Biochem. 244 16 PMID: 9025901

Williams et al (1999) Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3β and Shaggy. FEBS Lett. 448 86 PMID: 10217415

Keywords: 2B-(SP), 2B-(SP) supplier, Selective, GSK-3, phosphopeptide, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, Enzyme, Substrates, activators, 2BSP, /, Activators, Kinase, 1802, Tocris Bioscience

Citations for 2B-(SP)

Citations are publications that use Tocris products.

Currently there are no citations for 2B-(SP).

Reviews for 2B-(SP)

There are currently no reviews for this product. Be the first to review 2B-(SP) and earn rewards!

Have you used 2B-(SP)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review