Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review2B-(SP)
Description: Selective GSK-3 phosphopeptide substrate
Biological Activity for 2B-(SP)
2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3); derived from the phosphorylation site of the translation factor eIF2B.
Technical Data for 2B-(SP)
| M. Wt | 1835.88 |
| Formula | C71H123N26O29P |
| Sequence |
RRAAEELDSRAGSPQL (Modifications: Ser-13 = pSer) |
| Storage | Desiccate at -20°C |
| CAS Number | 186901-17-7 |
| PubChem ID | 90488714 |
| InChI Key | LBVCQYQHTKHZRY-APZQELAWSA-N |
| Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](COP(O)(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for 2B-(SP)
| Solubility | Soluble to 1 mg/ml in water |
Product Datasheets for 2B-(SP)
References for 2B-(SP)
References are publications that support the biological activity of the product.
Welsh et al (1997) Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal.Biochem. 244 16 PMID: 9025901
Williams et al (1999) Phosphorylated seryl and threonyl, but not tyrosyl, residues are efficient specificity determinants for GSK-3β and Shaggy. FEBS Lett. 448 86 PMID: 10217415
If you know of a relevant reference for 2B-(SP), please let us know.
View Related Products by Target
Keywords: 2B-(SP), 2B-(SP) supplier, Selective, GSK-3, phosphopeptide, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, Enzyme, Substrates, activators, 2BSP, /, Activators, Kinase, 1802, Tocris Bioscience
Citations for 2B-(SP)
Citations are publications that use Tocris products.
Currently there are no citations for 2B-(SP). Do you know of a great paper that uses 2B-(SP) from Tocris? Please let us know.
Reviews for 2B-(SP)
There are currently no reviews for this product. Be the first to review 2B-(SP) and earn rewards!
Have you used 2B-(SP)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image