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Phosphatases catalyze dephosphorylation. They are hydrolase enzymes that replace a phosphate group on the substrate with a hydroxyl group from water. The action of phosphatases are in direct opposition to those of kinases and phosphorylases. Dephosphorylation can activate or deactivate the substrate and enable or disable protein-protein interactions, thus they have an integral role in signal transduction pathways.
Tocris offers the following scientific literature for Phosphatases to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.