Phosphatases catalyze dephosphorylation. They are hydrolase enzymes that replace a phosphate group on the substrate with a hydroxyl group from water. The action of phosphatases are in direct opposition to those of kinases and phosphorylases. Dephosphorylation can activate or deactivate the substrate and enable or disable protein-protein interactions, thus they have an integral role in signal transduction pathways.
Phosphatases Target Files
Literature for Phosphatases
Tocris offers the following scientific literature for Phosphatases to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Metabolism Research Product Guide
This product guide reviews some of the main areas in cancer metabolism research and lists around 150 products that can be used to investigate metabolic pathways in cancer including:
- Tricarboxylic Acid Cycle
- 1C Metabolism and Nucleic Acid Synthesis
- Drivers of Metabolic Reprogramming
- pH and Redox Balance