Kisspeptin Receptor

The kisspeptin receptor (also known as the KISS1 receptor) is a G_q/G₁₁-protein-coupled receptor that signals through stimulation of phospholipase C. The kisspeptin receptor plays a key role in the neuroendocrine control of the gonadotrophin axis.

Products

Background

Literature (3)

Gene Data

Kisspeptin Receptor Agonists
Cat. No.	Product Name / Activity
7490	KISS1 305 New
	Kisspeptin1 receptor agonist
2570	Kisspeptin 10 (human)
	Endogenous ligand for kisspeptin receptor
4243	Kisspeptin 10 (rat)
	Endogenous ligand for kisspeptin receptor
1443	Metastin (human)
	Potent, endogenous ligand for kisspeptin receptor
Kisspeptin Receptor Antagonists
Cat. No.	Product Name / Activity
3881	Kisspeptin 234
	Kisspeptin receptor antagonist; kisspeptin 10 (Cat. No. 2570) analog

The kisspeptin receptor (also known as the KISS1 receptor) is a G_q/G₁₁-protein-coupled receptor that signals through stimulation of phospholipase C resulting in Ca²⁺ mobilization. The kisspeptin receptor is found at high concentrations in the pancreas, placenta and brain and there are lower expression levels in the small intestine, kidney, lung, liver and heart.

The kisspeptin receptor plays a key role in the neuroendocrine control of the gonadotrophin axis and has been implicated in the inhibition of metastasis. The human KISS1 receptor gene is localized on chromosome 19p13.3.

External sources of pharmacological information for Kisspeptin Receptor :

IUPHAR Receptor Code

BJP Guide

Literature for Kisspeptin Receptor

Tocris offers the following scientific literature for Kisspeptin Receptor to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

Cancer Metabolism
Epigenetics in Cancer
Receptor Signaling
Cell Cycle and DNA Damage Repair
Angiogenesis
Invasion and Metastasis

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

Rhodopsin-like Receptors
Glutamate Receptors
Frizzled Receptors
GPCR Signaling

Peptide Hormone Receptors Product Listing

A collection of over 200 products for peptide hormone receptors, the listing includes research tools for the study of:

Anterior Pituitary Regulation
Blood Pressure Regulation
Feeding and Appetite Regulation
Glucose Regulation
Peptide Hormone Processing