Kisspeptin Receptor
The kisspeptin receptor (also known as the KISS1 receptor) is a Gq/G11-protein-coupled receptor that signals through stimulation of phospholipase C. The kisspeptin receptor plays a key role in the neuroendocrine control of the gonadotrophin axis.
Agonists |
|
|---|---|
| Cat No | Product Name / Activity |
| 5347 | Kisspeptin 10 (dog) |
| Endogenous ligand for canine kisspeptin receptor | |
| 2570 | Kisspeptin 10 (human) |
| Endogenous ligand for kisspeptin receptor | |
| 4243 | Kisspeptin 10 (rat) |
| Endogenous ligand for kisspeptin receptor | |
| 1443 | Metastin (human) |
| Potent, endogenous ligand for kisspeptin receptor | |
Antagonists |
|
| Cat No | Product Name / Activity |
| 3881 | Kisspeptin 234 |
| Kisspeptin receptor antagonist; kisspeptin 10 (Cat. No. 2570) analog | |
The kisspeptin receptor (also known as the KISS1 receptor) is a Gq/G11-protein-coupled receptor that signals through stimulation of phospholipase C resulting in Ca2+ mobilization. The kisspeptin receptor is found at high concentrations in the pancreas, placenta and brain and there are lower expression levels in the small intestine, kidney, lung, liver and heart.
The kisspeptin receptor plays a key role in the neuroendocrine control of the gonadotrophin axis and has been implicated in the inhibition of metastasis. The human KISS1 receptor gene is localized on chromosome 19p13.3.
External sources of pharmacological information for Kisspeptin Receptor :
Literature for Kisspeptin Receptor
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