Cat. No. 4433
Alternative Name: SC1
Chemical Name: N-[3-[7-[(1,3-Dimethyl-1H-pyrazol-5
Biological ActivityDual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal. Enables propagation of undifferentiated murine ESCs in the absence of leukemia inhibitory factor (LIF).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Mertins et al (2013) A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept. PLoS One 8 e57099. PMID: 23437320.
Chen et al (2006) Self-renewal of embryonic stem cells by a small molecule. Proc.Natl.Acad.Sci.USA 103 17266. PMID: 17088537.
Wu and Ding et al (2006) Applying chemical tools to the discovery of novel regenerative medicine. Drug Discov.Today Technol. 3 255.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Pluripotin from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Pluripotin, supplier, dual, inhibitors, inhibits, extracellular, signal-regulated, kinase, 1, ERK1, MAPK3, mitogen-activated, protein, kinase, 3, RasGAP, mouse, murine, stem, cells, self-renewal, SC1, Tocris Bioscience, ERK Inhibitor products
Find multiple products by catalog number
New Products in this Area
Endogenous polyunsaturated fatty acid; stimulates ERK1/2 phosphorylationBIRB 796
High affinity and selective p38 kinase inhibitorPH 797804
Potent and selective p38α/β inhibitorDEL 22379
ERK dimerization inhibitor
December 13 - 15, 2016