Rac1 Inhibitor W56

Cat. No. 2221

Rac1 Inhibitor W56 Met-Val-Asp-Gly-Lys-Pro-Val-Asn-Leu-Gly-Leu-Trp-Asp-Thr-Ala-Gly

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Biological Activity

Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. Control peptide available (Cat. No. 2222).

Technical Data

M.Wt:
1671.93
Formula:
C74H117N19O23S
Sequence:
MVDGKPVNLGLWDTAG
Solubility:
Soluble to 2 mg/ml in PBS (pH 7.4)
Storage:
Desiccate at -20°C
CAS No:
1095179-01-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Gao et al (2001) Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J.Biol.Chem. 276 47530. PMID: 11595749.

If you know of a relevant reference for Rac1 Inhibitor W56 please let us know.

Citations are publications that use Tocris products. Selected citations for Rac1 Inhibitor W56 include:

Zeineddine et al (2015) SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Am J Physiol Lung Cell Mol Physiol 10 57. PMID: 26520394.

Do you know of a great paper that uses Rac1 Inhibitor W56 from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Rac1 Inhibitor W56, supplier, Selective, inhibitors, inhibits, Rac1-GEF, interaction, GTPases, G, Proteins, Small, Tocris Bioscience, G Protein (Small) Inhibitor products

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