Rac1 Inhibitor W56
Cat. No. 2221
Biological ActivityPeptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. Control peptide available (Cat. No. 2222).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Gao et al (2001) Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J.Biol.Chem. 276 47530. PMID: 11595749.
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Citations are publications that use Tocris products. Selected citations for Rac1 Inhibitor W56 include:
Zeineddine et al (2015) SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Am J Physiol Lung Cell Mol Physiol 10 57. PMID: 26520394.
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Keywords: Rac1 Inhibitor W56, supplier, Selective, inhibitors, inhibits, Rac1-GEF, interaction, GTPases, G, Proteins, Small, Tocris Bioscience, G Protein (Small) Inhibitor products
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