Zinc protoporphyrin IX
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 626.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.6 mL||7.99 mL||15.97 mL|
|5 mM||0.32 mL||1.6 mL||3.19 mL|
|10 mM||0.16 mL||0.8 mL||1.6 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497 PMID: 2890093
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997
Luo and Vincen (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol. 267 263 PMID: 7522180
Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381 PMID: 7678352
If you know of a relevant reference for Zinc protoporphyrin IX, please let us know.
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Keywords: Guanylyl cyclase inhibits inhibitors heme oxygenase Heme guanylyl sGC Cyclase Cyclases Oxygenase Oxidase Oxygenases Oxidases Zinc protoporphyrinIX Heme Oxygenase
Citations for Zinc protoporphyrin IX
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Literature in this Area
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Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
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