Zinc protoporphyrin IX
Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 626.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.6 mL||7.99 mL||15.97 mL|
|5 mM||0.32 mL||1.6 mL||3.19 mL|
|10 mM||0.16 mL||0.8 mL||1.6 mL|
|50 mM||0.03 mL||0.16 mL||0.32 mL|
References are publications that support the products' biological activity.
Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497 PMID: 2890093
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997
Luo and Vincen (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol. 267 263 PMID: 7522180
Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381 PMID: 7678352
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