Tin protoporphyrin IX dichloride

Discontinued Product

Tin protoporphyrin IX dichloride (Cat. No. 0747) has been withdrawn from sale for commercial reasons.
Description: Heme oxygenase inhibitor
Citations (3)

Biological Activity for Tin protoporphyrin IX dichloride

Tin protoporphyrin IX dichloride is a potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.

Technical Data for Tin protoporphyrin IX dichloride

M. Wt 750.25
Formula C34H32Cl2N4O4Sn
Storage Store at RT
CAS Number 14325-05-4
PubChem ID 3000478
Smiles C=CC1=C(/C=C3\N=C(/C=C(N5[Sn](Cl)6Cl)/C(C)=C(CCC(O)=O)/C5=C4)C(C=C)=C3C)N6C(/C=C2/C(C)=C(CCC(O)=O)C/4=N2)=C1C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Tin protoporphyrin IX dichloride

References for Tin protoporphyrin IX dichloride

References are publications that support the biological activity of the product.

Drummond and Kappas (1981) Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of haem oxidation. Proc.Natl.Acad.Sci.U.S.A. 78 6466 PMID: 6947237

Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997

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3 Citations for Tin protoporphyrin IX dichloride

Citations are publications that use Tocris products. Selected citations for Tin protoporphyrin IX dichloride include:

Guimarães et al (2012) Mitochondrial uncouplers inhibit hepatic stellate cell activation. BMC Gastroenterol 12 68 PMID: 22686625

Ye et al (2013) Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis. BMC Neurosci 13 156 PMID: 23272707

Duann et al (2019) Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes. Data Brief 22 279 PMID: 30591946

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