A potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 750.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.33 mL||6.66 mL||13.33 mL|
|5 mM||0.27 mL||1.33 mL||2.67 mL|
|10 mM||0.13 mL||0.67 mL||1.33 mL|
|50 mM||0.03 mL||0.13 mL||0.27 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Drummond and Kappas (1981) Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of haem oxidation. Proc.Natl.Acad.Sci.U.S.A. 78 6466 PMID: 6947237
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193 PMID: 9226997
If you know of a relevant reference for Tin protoporphyrin IX dichloride, please let us know.
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Keywords: Heme haem oxygenase inhibitors inhibits Oxygenases Oxidases Tin protoporphyrinIX dichloride Heme Oxygenase
2 Citations for Tin protoporphyrin IX dichloride
Citations are publications that use Tocris products. Selected citations for Tin protoporphyrin IX dichloride include:
Ye et al (2013) Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis. BMC Neurosci 13 156 PMID: 23272707
Guimarães et al (2012) Mitochondrial uncouplers inhibit hepatic stellate cell activation. BMC Gastroenterol 12 68 PMID: 22686625
Do you know of a great paper that uses Tin protoporphyrin IX dichloride from Tocris? If so please let us know.
Literature in this Area
New Product Guide (Spring/Summer 2017)New
Our new product guide highlights over 130 new products added to the Tocris Bioscience range during the first half of 2017.
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