Non-benzodiazepine agent that acts as an agonist at the benzodiazepine site. Displays hypnotic, anxiolytic, myorelaxant and anticonvulsant activity.
|Storage||Desiccate at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 305.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.28 mL||16.38 mL||32.75 mL|
|5 mM||0.66 mL||3.28 mL||6.55 mL|
|10 mM||0.33 mL||1.64 mL||3.28 mL|
|50 mM||0.07 mL||0.33 mL||0.66 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Gaudreault et al (1995) Pharmacokinetics and anticonvulsant effect of a new hypnotic, CL 284,846, in rats. Pharm.Res. 12 1592 PMID: 8592655
Sanger et al (1996) Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem. Eur.J.Pharmacol. 313 35 PMID: 8905326
If you know of a relevant reference for Zaleplon, please let us know.
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Keywords: Benzodiazepine agonists GABAA Receptors CL284846 CL 284846 GABAA Receptors
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