Zaleplon

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Cat.No. 3655 - Zaleplon | C17H15N5O | CAS No. 151319-34-5
Description: Benzodiazepine site agonist
Alternative Names: CL 284846
Chemical Name: N-[3-(Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide
Purity: ≥99% (HPLC)
Datasheet
Citations

Biological Activity

Non-benzodiazepine agent that acts as an agonist at the benzodiazepine site. Displays hypnotic, anxiolytic, myorelaxant and anticonvulsant activity.

Technical Data

M. Wt 305.33
Formula C17H15N5O
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 151319-34-5
PubChem ID 5719
InChI Key HUNXMJYCHXQEGX-UHFFFAOYSA-N
Smiles CC(N(CC)C1=CC=CC(C3=CC=NC2=C(C#N)C=NN23)=C1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.53 100
ethanol 3.05 10

Preparing Stock Solutions

The following data is based on the product molecular weight 305.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.28 mL 16.38 mL 32.75 mL
5 mM 0.66 mL 3.28 mL 6.55 mL
10 mM 0.33 mL 1.64 mL 3.28 mL
50 mM 0.07 mL 0.33 mL 0.66 mL

Molarity Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Gaudreault et al (1995) Pharmacokinetics and anticonvulsant effect of a new hypnotic, CL 284,846, in rats. Pharm.Res. 12 1592 PMID: 8592655

Sanger et al (1996) Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem. Eur.J.Pharmacol. 313 35 PMID: 8905326


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