Vanilloid TRPV1 Receptor Tocriset™

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Contents of Tocriset:

Cat.No. Product Name / Activity
0462(E)-Capsaicin
prototypic vanilloid receptor agonist
0464Capsazepine
vanilloid receptor antagonist
0934Olvanil
potent vanilloid receptor agonist
1615SB 366791
potent, selective, competitive TRPV1 antagonist
1641OLDA
potent vanilloid TRPV1 receptor agonist
Description: Selection of 5 vanilloid TRPV1 receptor ligands (Cat. Nos. 0462, 0934, 1137, 0464 and 1615)
Datasheet
Citations
Literature

Biological Activity

Contains the listed products as lyophilised solids which can be used to investigate the pharmacology of vanilloid TRPV1 receptors.

Technical Data

Tocrisets contain 3-5 ligands supplied as lyophilized solids or pre-dissolved in DMSO at a specified concentration. Lyophilized solids have been freeze-dried (approximately 0.5-2 mg per vial) so that addition of 0.5 or 1 ml of solvent produces a stock concentration of 10 or 5 mM respectively.

Please see individual product listings for specific technical data and certificate of analysis.

Technical Data

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

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View all TRPV Ligand Sets

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Citations for Vanilloid TRPV1 Receptor Tocriset™

Citations are publications that use Tocris products.

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Literature in this Area

Pain

Pain Research Product Guide

A collection of over 250 products for pain research, the guide includes research tools for the study of:

  • Nociception
  • Ion Channels
  • G-Protein-Coupled Receptors
  • Intracellular Signaling
Pain

Pain Poster

Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.