UK 59811 hydrochloride

Discontinued Product

UK 59811 hydrochloride (Cat. No. 6179) has been withdrawn from sale for commercial reasons.
Description: CaVAb blocker
Chemical Name: 3-Ethyl 5-methyl 4-(2-bromophenyl)-2-((2-(dimethylamino)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
Purity: ≥98% (HPLC)

Biological Activity for UK 59811 hydrochloride

UK 59811 hydrochloride is a blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data for UK 59811 hydrochloride

M. Wt 517.84
Formula C22H29BrN2O5.HCl
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 2250025-89-7
PubChem ID 134812832
Smiles CCOC(C1=C(NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Br)COCCN(C)C)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for UK 59811 hydrochloride

References for UK 59811 hydrochloride

References are publications that support the biological activity of the product.

Tang et al (2016) Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs. Nature 537 117 PMID: 27556947

View Related Products by Product Action

View all Non-selective Cav Channel Blockers

Keywords: UK 59811 hydrochloride, UK 59811 hydrochloride supplier, UK59811, HCl, hydrochloride, voltage-gated, calcium, channels, blockers, blocks, inhibits, inhibitors, CavAb, Ca2+, 102672-02-6, NavAb, Non-selective, Cav, Channels, Voltage-gated, Sodium, 6179, Tocris Bioscience

Citations for UK 59811 hydrochloride

Citations are publications that use Tocris products.

Currently there are no citations for UK 59811 hydrochloride.

Reviews for UK 59811 hydrochloride

There are currently no reviews for this product. Be the first to review UK 59811 hydrochloride and earn rewards!

Have you used UK 59811 hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review