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Submit ReviewUK 59811 hydrochloride is a blocks CaVAb, a site-directed mutant of bacterial NaVAb with full voltage-dependent Ca2+ channel function (IC50 = 194 nM).
Sold for research purposes under agreement from Pfizer Inc.
M. Wt | 517.84 |
Formula | C22H29BrN2O5.HCl |
Storage | Store at +4°C |
Purity | ≥98% (HPLC) |
CAS Number | 2250025-89-7 |
PubChem ID | 134812832 |
InChI Key | JZOQTVYILXBAMQ-UHFFFAOYSA-N |
Smiles | CCOC(C1=C(NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Br)COCCN(C)C)=O.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Tang et al (2016) Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs. Nature 537 117 PMID: 27556947
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