SB 221284

Discontinued Product

SB 221284 (Cat. No. 1379) has been withdrawn from sale for commercial reasons.
Cat.No. 1379 - SB 221284 | C16H14F3N3OS | CAS No. 196965-14-7
Description: Potent and selective 5-HT2B and 5-HT2C antagonist
Chemical Name: 2,3-Dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-1H-indole-1-carboxamide
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (4)

Biological Activity for SB 221284

SB 221284 is a potent, selective 5-HT2C/2B receptor antagonist. pKi values are 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo.

Licensing Information

Sold under license

Technical Data for SB 221284

M. Wt 353.36
Formula C16H14F3N3OS
Storage Store at +4°C
Purity ≥99% (HPLC)
CAS Number 196965-14-7
PubChem ID 443389
InChI Key OQZOXHCRSXYSPM-UHFFFAOYSA-N
Smiles CSC1=C(C=C2N(CCC2=C1)C(=O)NC1=CC=CN=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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Keywords: SB 221284, SB 221284 supplier, Potent, selective, 5-HT2C, antagonists, Serotonin, Receptors, 5-HT2B, SB221284, 1379, Tocris Bioscience

Citations for SB 221284

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Literature in this Area

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