Quinine hydrochloride

Pricing Availability   Qty
Description: Antimalarial
Chemical Name: (R)-(6-Methoxyquinolin-4-yl)((2S,4S,8R)- 8-vinylquinuclidin-2-yl)methanol hydrochloride
Datasheet
Citations (1)
Reviews (1)

Biological Activity for Quinine hydrochloride

Quinine hydrochloride displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine (Cat. No. 4108); closely related to chloroquine (Cat. No. 4109).

Technical Data for Quinine hydrochloride

M. Wt 360.88
Formula C20H24N2O2.HCl
Storage Store at -20°C
CAS Number 130-89-2
PubChem ID 23424067
InChI Key LBSFSRMTJJPTCW-CYAVNPPASA-N
Smiles O[C@@H](C3N(CC4C=C)CCC4C3)C2=CC=NC1=CC=C(OC)C=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Quinine hydrochloride

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 36.09 100
DMSO 36.09 100

Preparing Stock Solutions for Quinine hydrochloride

The following data is based on the product molecular weight 360.88. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.77 mL 13.86 mL 27.71 mL
5 mM 0.55 mL 2.77 mL 5.54 mL
10 mM 0.28 mL 1.39 mL 2.77 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets for Quinine hydrochloride

Certificate of Analysis / Product Datasheet
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References for Quinine hydrochloride

References are publications that support the biological activity of the product.

Merck Index 14 8061


If you know of a relevant reference for Quinine hydrochloride, please let us know.

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Keywords: Quinine hydrochloride, Quinine hydrochloride supplier, antimalarial, muscle, relaxant, Antimalarials, 4114, Tocris Bioscience

1 Citation for Quinine hydrochloride

Citations are publications that use Tocris products. Selected citations for Quinine hydrochloride include:

Kawai et al (2022) Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion. Nat.Commun. 13 7708 PMID: 36550097


Do you know of a great paper that uses Quinine hydrochloride from Tocris? Please let us know.

Reviews for Quinine hydrochloride

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Quinine was used along with penicillin derivatives to treat co-existance of malaria.
By Anonymous on 02/20/2019
Species: Human

Use of antibacterials and antimalarials is common in the tropics because malaria is frequently associated with other infections.Quinine was used along with penicillin derivatives to treat co-existance of malaria.

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