Discontinued Product

Primidone (Cat. No. 0830) has been withdrawn from sale for commercial reasons.
Description: Potentiates GABAA receptor function
Chemical Name: 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione
Literature (2)

Biological Activity for Primidone


Technical Data for Primidone

M. Wt 218.25
Formula C12H14N2O2
Storage Store at RT
CAS Number 125-33-7
PubChem ID 4909
Smiles CCC1(C(=O)NCNC1=O)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Primidone

References are publications that support the biological activity of the product.

Loscher and Honack (1989) Comparison of the anticonvulsant efficacy of PrimiD and phenobarbital during chronic treatment of amygdala-kindled rats. Eur.J.Pharmacol. 162 309 PMID: 2721568

Merck Index 12 7927

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Keywords: Primidone, Primidone supplier, Potentiates, GABAA, receptor, function, Receptors, 0830, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Primidone, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to

Citations for Primidone

Citations are publications that use Tocris products.

Currently there are no citations for Primidone.

Reviews for Primidone

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.

Addiction Poster

Addiction Poster

The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.