Primidone

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Cat.No. 0830 - Primidone | C12H14N2O2 | CAS No. 125-33-7
Description: Potentiates GABAA receptor function
Chemical Name: 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione
Datasheet
Citations
Literature

Biological Activity

Anticonvulsant.

Technical Data

M. Wt 218.25
Formula C12H14N2O2
Storage Store at RT
CAS Number 125-33-7
PubChem ID 4909
InChI Key DQMZLTXERSFNPB-UHFFFAOYSA-N
Smiles CCC1(C(=O)NCNC1=O)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 21.82 100

Preparing Stock Solutions

The following data is based on the product molecular weight 218.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.58 mL 22.91 mL 45.82 mL
5 mM 0.92 mL 4.58 mL 9.16 mL
10 mM 0.46 mL 2.29 mL 4.58 mL
50 mM 0.09 mL 0.46 mL 0.92 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Loscher and Honack (1989) Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats. Eur.J.Pharmacol. 162 309 PMID: 2721568

Merck Index 12 7927 PMID:


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Keywords: Potentiates GABAA receptor function Receptors GABAA Receptors

Citations for Primidone

Citations are publications that use Tocris products.

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Reviews

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Literature in this Area

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Pathways for Primidone

Protocols

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