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Cat.No. 6385 - Phenanthroline | C12H8N2 | CAS No. 66-71-7
Description: Enhances hPSC differentiation into cranial placode cells
Chemical Name: 1,10-Phenanthroline
Purity: ≥99% (HPLC)

Biological Activity

Enhances hPSC differentiation into cranial placode cells. Induces a 5-fold increase in cells expressing SIX1.

Technical Data

M. Wt 180.21
Formula C12H8N2
Storage Desiccate at RT
Purity ≥99% (HPLC)
CAS Number 66-71-7
PubChem ID 1318
Smiles C12=CC=C3C=CC=NC3=C1N=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 18.02 100
ethanol 18.02 100

Preparing Stock Solutions

The following data is based on the product molecular weight 180.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.55 mL 27.75 mL 55.49 mL
5 mM 1.11 mL 5.55 mL 11.1 mL
10 mM 0.55 mL 2.77 mL 5.55 mL
50 mM 0.11 mL 0.55 mL 1.11 mL

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References are publications that support the products' biological activity.

Tchieu et al (2017) A modular platform for differentiation of human PSCs into all major ectodermal lineages. Cell Stem Cell 21 399 PMID: 28886367

If you know of a relevant reference for Phenanthroline, please let us know.

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Keywords: Phenanthroline, supplier, stem, cells, human, pluripotent, differentiation, cranial, placode, SIX1, Neural, Stem, Cells, Neural, Stem, Cells, Tocris Bioscience

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