MRE11 endonuclease inhibitor. Prevents double-stranded break (DSB) resection. Enhances non-homologous end-joining (NHEJ) and reduces homologous recombination.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 293.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.41 mL||17.04 mL||34.08 mL|
|5 mM||0.68 mL||3.41 mL||6.82 mL|
|10 mM||0.34 mL||1.7 mL||3.41 mL|
|50 mM||0.07 mL||0.34 mL||0.68 mL|
References are publications that support the products' biological activity.
Shibata et al (2014) DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol.Cell 53 7 PMID: 24316220
If you know of a relevant reference for PFM 01, please let us know.
View Related Products by Product Action
Keywords: PFM 01, supplier, PFM01, MRE11, meiotic, recombination, 11, homolog, A, endonuclease, inhibitors, inhibits, non-homologous, end-joining, NHEJ, recombination, HR, DNA,, RNA, and, Protein, Synthesis, DNA,, RNA, and, Protein, Synthesis, Tocris Bioscience
Citations for PFM 01
Citations are publications that use Tocris products.
Currently there are no citations for PFM 01. Do you know of a great paper that uses PFM 01 from Tocris? If so please let us know.
Reviews for PFM 01
There are currently no reviews for this product. Be the first to review PFM 01 and earn rewards!
Have you used PFM 01?
Submit a review and receive an Amazon gift card.
$10US/$10CAN/€7/£6 gift card for a review without an image
$25US/$25CAN/€18/£15 gift card for a review with an image
*Offer only valid in the USA / Canada, UK and EuropeSubmit a Review