Pam2CSK4 Biotin

Pricing Availability Delivery Time Qty
Cat.No. 4638 - Pam2CSK4 Biotin | Pam2-Cys-Ser-Lys-Lys-Lys-Lys-Aca-Aca-Biotin
Description: Biotinylated Pam2CSK4 (Cat. No. 4637)
Datasheet
Citations
Reviews
Literature
Pathways

Biological Activity

Biotinylated Pam2CSK4 (Cat. No. 4637), a Toll-like receptor 2/6 agonist.

Technical Data

M. Wt 1724.44
Formula C87H162N14O16S2
Sequence CSKKKK

(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys), K6= aminocaproic acid-amonocaproic acid-biotin

Storage Store at -20°C
PubChem ID 90488960
InChI Key PGEYKKZJERUKGD-ZMWMYQNNSA-N
Smiles [H]N[C@@H](CSC[C@@H](COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H])C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 1 mg/ml in 20% acetonitrile - 0.1% acetic acid

Preparing Stock Solutions

The following data is based on the product molecular weight 1724.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.58 mL 2.9 mL 5.8 mL
5 mM 0.12 mL 0.58 mL 1.16 mL
10 mM 0.06 mL 0.29 mL 0.58 mL
50 mM 0.01 mL 0.06 mL 0.12 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the biological activity of the product.

Latz et al (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nat.Immunol. 8 772 PMID: 17572678


If you know of a relevant reference for Pam2CSK4 Biotin, please let us know.

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Keywords: Pam2CSK4 Biotin, Pam2CSK4 Biotin supplier, biotinylated, Pam2CSK4, TLR2, TLR6, agonists, Toll-like, receptors, Receptors, 4638, Tocris Bioscience

Citations for Pam2CSK4 Biotin

Citations are publications that use Tocris products.

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Cancer

Cancer Research Product Guide

A collection of over 750 products for cancer research, the guide includes research tools for the study of:

  • Cancer Metabolism
  • Epigenetics in Cancer
  • Receptor Signaling
  • Cell Cycle and DNA Damage Repair
  • Angiogenesis
  • Invasion and Metastasis
Immunology

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation

Pathways for Pam2CSK4 Biotin

Toll-like Receptor

Toll-like Receptor Signaling Pathway

TLR signaling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.