Pam2CSK4 Biotin

Discontinued Product

Pam2CSK4 Biotin (Cat. No. 4638) has been withdrawn from sale for commercial reasons.
Description: Biotinylated Pam2CSK4 (Cat. No. 4637)
Datasheet
Citations
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Pathways (1)

Biological Activity for Pam2CSK4 Biotin

Pam2CSK4 Biotin is a biotinylated Pam2CSK4 (Cat. No. 4637), a Toll-like receptor 2/6 agonist.

Technical Data for Pam2CSK4 Biotin

M. Wt 1724.44
Formula C87H162N14O16S2
Sequence CSKKKK

(Modifications: Cys = S-[2,3-Bis(palmitoyloxy)-(2-R)-propyl]-Cys), K6= aminocaproic acid-amonocaproic acid-biotin

Storage Store at -20°C
PubChem ID 90488960
InChI Key PGEYKKZJERUKGD-ZMWMYQNNSA-N
Smiles [H]N[C@@H](CSC[C@@H](COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@]2([H])NC(=O)N[C@]12[H])C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Pam2CSK4 Biotin

References for Pam2CSK4 Biotin

References are publications that support the biological activity of the product.

Latz et al (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nat.Immunol. 8 772 PMID: 17572678

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Keywords: Pam2CSK4 Biotin, Pam2CSK4 Biotin supplier, biotinylated, Pam2CSK4, TLR2, TLR6, agonists, Toll-like, receptors, Receptors, 4638, Tocris Bioscience

Citations for Pam2CSK4 Biotin

Citations are publications that use Tocris products.

Currently there are no citations for Pam2CSK4 Biotin.

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Pathways for Pam2CSK4 Biotin

Toll-like Receptor Signaling Pathway

Toll-like Receptor Signaling Pathway

TLR signaling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.