Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewOxycodone hydrochloride
Discontinued Product
Oxycodone hydrochloride (Cat. No. 3958) has been withdrawn from sale for commercial reasons.
Description: μ agonist
Chemical Name: (5α)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride
Purity: ≥99% (HPLC)
Biological Activity for Oxycodone hydrochloride
Potent and selective μ-opioid receptor agonist (Ki values are 16 and >1000 nM for hMOR1 and hKOR1 respectively).
Technical Data for Oxycodone hydrochloride
| M. Wt | 351.82 |
| Formula | C18H21NO4.HCl |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 124-90-3 |
| PubChem ID | 5462350 |
| InChI Key | MUZQPDBAOYKNLO-RKXJKUSZSA-N |
| Smiles | O=C3[C@H]5[C@]24C1=C(O5)C(OC)=CC=C1C[C@@H](N(C)CC4)[C@@](O)2CC3.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Oxycodone hydrochloride
References for Oxycodone hydrochloride
References are publications that support the biological activity of the product.
Lalovic et al (2006) Pharmacokinetics and pharmacodynamics of oral oxyc. in healthy human subjects: role of circulating active metabolites. Clin.Pharmacol.Ther. 79 461 PMID: 16678548
View Related Products by Target
View Related Products by Product Action
Keywords: Oxycodone hydrochloride, Oxycodone hydrochloride supplier, agonists, μ1-opioid, mu1-opioid, Receptors, MOP, μ-opioid, mu-opioid, Mu, Opioid, 3958, Tocris Bioscience
1 Citation for Oxycodone hydrochloride
Citations are publications that use Tocris products. Selected citations for Oxycodone hydrochloride include:
Brock et al (2017) Assessing the Value of the Zebrafish Conditioned Place Preference Model for Predicting Human Abuse Potential. J Pharmacol Exp Ther 363 66 PMID: 28790193
Reviews for Oxycodone hydrochloride
There are currently no reviews for this product. Be the first to review Oxycodone hydrochloride and earn rewards!
Have you used Oxycodone hydrochloride?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
GPCR Product Listing
A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:
- Rhodopsin-like Receptors
- Glutamate Receptors
- Frizzled Receptors
- GPCR Signaling
Pain Research Product Guide
A collection of over 280 products for pain research, the guide includes research tools for the study of:
- Nociception
- Ion Channels
- G-Protein-Coupled Receptors
- Intracellular Signaling
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Pain Poster
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.