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Discontinued ProductOxycodone hydrochloride (Cat. No. 3958) has been withdrawn from sale for commercial reasons.
Biological Activity for Oxycodone hydrochloride
Potent and selective μ-opioid receptor agonist (Ki values are 16 and >1000 nM for hMOR1 and hKOR1 respectively).
Technical Data for Oxycodone hydrochloride
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Oxycodone hydrochloride
References for Oxycodone hydrochloride
References are publications that support the biological activity of the product.
Lalovic et al (2006) Pharmacokinetics and pharmacodynamics of oral oxyc. in healthy human subjects: role of circulating active metabolites. Clin.Pharmacol.Ther. 79 461 PMID: 16678548
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Keywords: Oxycodone hydrochloride, Oxycodone hydrochloride supplier, agonists, μ1-opioid, mu1-opioid, Receptors, MOP, μ-opioid, mu-opioid, Mu, Opioid, 3958, Tocris Bioscience
1 Citation for Oxycodone hydrochloride
Citations are publications that use Tocris products. Selected citations for Oxycodone hydrochloride include:
Brock et al (2017) Assessing the Value of the Zebrafish Conditioned Place Preference Model for Predicting Human Abuse Potential. J Pharmacol Exp Ther 363 66 PMID: 28790193
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Peripheral sensitization is the reduction in the threshold of excitability of sensory neurons that results in an augmented response to a given external stimulus. This poster outlines the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. The role of ion channels, GPCRs, neurotrophins, and cytokines in sensory neurons are also described.