Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3 receptor activation but stimulates transport when oxidized by MAO. Also activates human α2A receptors, inhibiting subsequent cAMP production.
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 189.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.27 mL||26.37 mL||52.73 mL|
|5 mM||1.05 mL||5.27 mL||10.55 mL|
|10 mM||0.53 mL||2.64 mL||5.27 mL|
|50 mM||0.11 mL||0.53 mL||1.05 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Airriess et al (1997) Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A-adrenoceptor. Br.J.Pharmacol. 122 191 PMID: 9313925
Roeder (1999) Octopamine in invertebrates. Prog.Neurobiol. 59 533 PMID: 10515667
Visentin et al (2001) Dual action of octopamine on glucose transport into adipocytes: inhibition via β3-adrenoceptor activation and stimulation via oxidation by amine oxidases. J.Pharmacol.Exp.Ther. 299 96 PMID: 11561068
If you know of a relevant reference for Octopamine hydrochloride, please let us know.
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Keywords: Invertebrate biogenic amine activates β3-adrenoceptors β3-adrenoceptor b3-adrenoceptors alpha2A-adrenoceptors a2a-adrenoceptors a2a-adrenergic alpha2a-adrenergic β3-adrenergic b3-adrenergic Receptors TAAR1 (±)-p-Octopamine Epirenor Norfen Adrenergic Beta-3 Receptors
Citations for Octopamine hydrochloride
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