You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Dynamin inhibitor (IC50 = 1.9 μM for dynamin I). Inhibits receptor-mediated endocytosis (IC50 = 16 μM). Displays similar activity to MitMAB (Cat. No. 4224).
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 392.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.55 mL||12.74 mL||25.48 mL|
|5 mM||0.51 mL||2.55 mL||5.1 mL|
|10 mM||0.25 mL||1.27 mL||2.55 mL|
|50 mM||0.05 mL||0.25 mL||0.51 mL|
References are publications that support the biological activity of the product.
Quan et al (2007) Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol.Pharmacol. 72 1425 PMID: 17702890
Joshi et al (2010) The dynamin inhibitors MitMAB and OctMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells. Mol.Cancer Ther. 9 1995 PMID: 20571068
If you know of a relevant reference for OctMAB, please let us know.
View Related Products by Product Action
Keywords: OctMAB, OctMAB supplier, dynamin, I, II, inhibitors, inhibits, gtpase, endocytosis, OctMAB, Mitosis, Dynamin, 4225, Tocris Bioscience
1 Citation for OctMAB
Citations are publications that use Tocris products. Selected citations for OctMAB include:
Ford et al (2018) Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathog 14 e1007051 PMID: 29727463
Do you know of a great paper that uses OctMAB from Tocris? Please let us know.
Reviews for OctMAB
There are currently no reviews for this product. Be the first to review OctMAB and earn rewards!
Have you used OctMAB?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
New Product Guide (Fall/Winter 2018/2019)
Our new product guide highlights over 190 new products added to the Tocris Bioscience range during the second half of 2018.
- 7-TM Receptors
- Enzyme-Linked Receptors
- Ion Channels
- Nuclear Receptors
- Fluorescent Imaging
- Signal Transduction
- Stem Cells