o-3M3FBS

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Cat.No. 1942 - o-3M3FBS | C16H16F3NO2S | CAS No. 313981-55-4
Description: Inactive analog of m-3M3FBS (Cat. No. 1941)
Chemical Name: 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥99% (HPLC)
Datasheet
Citations (5)
Reviews
Literature

Biological Activity

Inactive analog of m-3M3FBS. Used as a negative control.

Active Analog also available.

Compound Libraries

o-3M3FBS is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 343.36
Formula C16H16F3NO2S
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 313981-55-4
PubChem ID 770820
InChI Key SKJJIFRWCCSXGL-UHFFFAOYSA-N
Smiles CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
ethanol 34.34 100
DMSO 34.34 100

Preparing Stock Solutions

The following data is based on the product molecular weight 343.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL
10 mM 0.29 mL 1.46 mL 2.91 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Molarity Calculator

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References

References are publications that support the biological activity of the product.

Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532


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Keywords: o-3M3FBS, o-3M3FBS supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipase, 1942, Tocris Bioscience

5 Citations for o-3M3FBS

Citations are publications that use Tocris products. Selected citations for o-3M3FBS include:

Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190

Szebenyi et al (2014) Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons. Front Cell Neurosci 8 336 PMID: 25374507

Wilke et al (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5 5540 PMID: 25420509

Horowitz et al (2005) Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. PLoS One 126 243 PMID: 16129772

Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol 143 3 PMID: 15302681


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Literature in this Area

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