o-3M3FBS
Biological Activity
Inactive analog of m-3M3FBS. Used as a negative control.
Active Analog also available.
Compound Libraries
o-3M3FBS is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 343.36 |
| Formula | C16H16F3NO2S |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 313981-55-4 |
| PubChem ID | 770820 |
| InChI Key | SKJJIFRWCCSXGL-UHFFFAOYSA-N |
| Smiles | CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 34.34 | 100 | |
| DMSO | 34.34 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 343.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.91 mL | 14.56 mL | 29.12 mL |
| 5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.91 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532
If you know of a relevant reference for o-3M3FBS, please let us know.
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Keywords: o-3M3FBS, supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipases, Phospholipase, C, Phospholipases, Tocris Bioscience
4 Citations for o-3M3FBS
Citations are publications that use Tocris products. Selected citations for o-3M3FBS include:
Wilke et al (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5 5540 PMID: 25420509
Horowitz et al (2005) Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. PLoS One 126 243 PMID: 16129772
Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol 143 3 PMID: 15302681
Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190
Do you know of a great paper that uses o-3M3FBS from Tocris? If so please let us know.
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