o-3M3FBS

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Cat.No. 1942 - o-3M3FBS | C16H16F3NO2S | CAS No. 313981-55-4
Description: Inactive analog of m-3M3FBS (Cat. No. 1941)
Chemical Name: 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥99% (HPLC)
Datasheet
Citations (3)
Literature

Biological Activity

Inactive analog of m-3M3FBS (Cat. No. 1941). Used as a negative control.

Compound Libraries

o-3M3FBS is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt 343.36
Formula C16H16F3NO2S
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 313981-55-4
PubChem ID 770820
InChI Key SKJJIFRWCCSXGL-UHFFFAOYSA-N
Smiles CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 34.34 100
ethanol 34.34 100

Preparing Stock Solutions

The following data is based on the product molecular weight 343.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL
10 mM 0.29 mL 1.46 mL 2.91 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532


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Keywords: o-3M3FBS, supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipases, Tocris Bioscience

3 Citations for o-3M3FBS

Citations are publications that use Tocris products. Selected citations for o-3M3FBS include:

Horowitz et al (2005) Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. PLoS One 126 243 PMID: 16129772

Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol 143 3 PMID: 15302681

Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190


Do you know of a great paper that uses o-3M3FBS from Tocris? If so please let us know.

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Literature in this Area

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Pathways for o-3M3FBS

Protocols

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