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Description: Inactive analog of m-3M3FBS (Cat. No. 1941)
Chemical Name: 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥99% (HPLC)
Citations (6)

Biological Activity for o-3M3FBS

o-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control.

Active Analog also available.

Compound Libraries for o-3M3FBS

o-3M3FBS is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for o-3M3FBS

M. Wt 343.36
Formula C16H16F3NO2S
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 313981-55-4
PubChem ID 770820
Smiles CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for o-3M3FBS

Solvent Max Conc. mg/mL Max Conc. mM
ethanol 34.34 100
DMSO 34.34 100

Preparing Stock Solutions for o-3M3FBS

The following data is based on the product molecular weight 343.36. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL
10 mM 0.29 mL 1.46 mL 2.91 mL
50 mM 0.06 mL 0.29 mL 0.58 mL

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References for o-3M3FBS

References are publications that support the biological activity of the product.

Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532

If you know of a relevant reference for o-3M3FBS, please let us know.

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Keywords: o-3M3FBS, o-3M3FBS supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipase, 1942, Tocris Bioscience

6 Citations for o-3M3FBS

Citations are publications that use Tocris products. Selected citations for o-3M3FBS include:

Wilke et al (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5 5540 PMID: 25420509

Szebenyi et al (2014) Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons. Front Cell Neurosci 8 336 PMID: 25374507

Carim et al (2019) IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol 29 775 PMID: 30799246

Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190

Do you know of a great paper that uses o-3M3FBS from Tocris? Please let us know.

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